TYROBP and KLRC4

Number of citations of the paper that reports this interaction (PMID 12426564)
74

Data Source:
HPRD (in vivo)

		TYROBP	KLRC4
Gene Name		TYRO protein tyrosine kinase binding protein	killer cell lectin-like receptor subfamily C, member 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface	Integral Component Of Membrane
	Molecular Function	Receptor Signaling Protein Activity Receptor Binding Protein Binding Identical Protein Binding
	Biological Process	Macrophage Activation Involved In Immune Response Neutrophil Activation Involved In Immune Response Cellular Defense Response Signal Transduction Integrin-mediated Signaling Pathway Axon Guidance Intracellular Signal Transduction Innate Immune Response Regulation Of Immune Response Regulation Of Osteoclast Development	Cellular Defense Response
Pathways		DAP12 signaling DAP12 interactions Axon guidance Semaphorin interactions Other semaphorin interactions Signal regulatory protein (SIRP) family interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS			Behcet's disease ( 23291587)
Protein-Protein Interactions		13 interactors: CD300E CLEC5A KIR3DS1 KLRC3 KLRC4 KLRK1 NCR2 SIGLEC14 SIRPB1 SYK TREM1 TREM2 ZAP70	4 interactors: MICB RAE1 TYROBP ULBP1
Entrez ID		7305	8302
HPRD ID		04996	16008
Ensembl ID		ENSG00000011600	ENSG00000183542
Uniprot IDs		O43914	O43908
PDB IDs		2L34 2L35
Enriched GO Terms of Interacting Partners?		Defense Response Innate Immune Response Immune Response Response To Stress Immune System Process Cellular Defense Response Beta Selection Positive Regulation Of Calcium-mediated Signaling Response To Stimulus Regulation Of Calcium-mediated Signaling Positive Regulation Of Alpha-beta T Cell Proliferation Lymphocyte Activation Leukocyte Activation Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Peptidyl-tyrosine Autophosphorylation Leukocyte Migration T Cell Selection Positive Regulation Of Alpha-beta T Cell Differentiation Hemopoiesis Positive Regulation Of Cell-cell Adhesion Cellular Response To Stimulus Signal Transduction Locomotion Neutrophil Chemotaxis Neutrophil Migration Cell Activation Immune System Development Response To Other Organism Granulocyte Chemotaxis Regulation Of T Cell Activation Positive Regulation Of Cell Activation Natural Killer Cell Activation Alpha-beta T Cell Differentiation Response To Biotic Stimulus Positive Regulation Of CD40 Signaling Pathway Cytokine Secretion Involved In Immune Response Detection Of Lipoteichoic Acid Positive Regulation Of C-C Chemokine Receptor CCR7 Signaling Pathway Signaling Alpha-beta T Cell Activation Leukocyte Differentiation Cell Communication Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Differentiation Positive Regulation Of Cytokine Secretion Positive Regulation Of Immune System Process Regulation Of Lymphocyte Activation	Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Leukocyte Activation Cell Activation Innate Immune Response Regulation Of Immune Response Immune Response Regulation Of Immune System Process Defense Response Leukocyte Mediated Immunity Antigen Processing And Presentation Regulation Of Osteoclast Development Gamma-delta T Cell Activation Neutrophil Activation Involved In Immune Response Negative Regulation Of Defense Response To Virus By Host Lymphocyte Activation Macrophage Activation Involved In Immune Response T Cell Mediated Cytotoxicity Immune System Process Viral Process Neutrophil Activation Cytolysis Negative Regulation Of Defense Response To Virus Macrophage Activation Regulation Of Defense Response To Virus By Host T Cell Mediated Immunity Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Cell Surface Receptor Signaling Pathway Cellular Defense Response Natural Killer Cell Activation Response To Stress Nuclear Envelope Organization MRNA Export From Nucleus Regulation Of Osteoclast Differentiation Glucose Transport RNA Export From Nucleus Hexose Transport Regulation Of Defense Response To Virus Response To Stimulus
Tagcloud ?		acts ad adaptor articles beta1 complement concerning convincing cr3 dendritic elusive emerging introduce meanwhile microglia opportunities osteoclasts participate participates pathogenesis phagocytic piece playing repression sirpbeta1 speculate trem2 triggering
Tagcloud (Difference) ?		acts ad adaptor articles beta1 complement concerning convincing cr3 dendritic elusive emerging introduce meanwhile microglia opportunities osteoclasts participate participates pathogenesis phagocytic piece playing repression sirpbeta1 speculate trem2 triggering
Tagcloud (Intersection) ?