KLRC4 and MICB

Number of citations of the paper that reports this interaction (PMID 12133964)
9

Data Source:
HPRD (in vitro)

		KLRC4	MICB
Gene Name		killer cell lectin-like receptor subfamily C, member 4	MHC class I polypeptide-related sequence B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function		Antigen Binding Beta-2-microglobulin Binding Natural Killer Cell Lectin-like Receptor Binding
	Biological Process	Cellular Defense Response	T Cell Mediated Cytotoxicity Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Oxidative Stress Response To Heat Viral Process Cytolysis Antigen Processing And Presentation Response To Retinoic Acid Natural Killer Cell Mediated Cytotoxicity Gamma-delta T Cell Activation Negative Regulation Of Defense Response To Virus By Host Regulation Of Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS		Behcet's disease ( 23291587)	AIDS progression ( 19115949) Behcet's disease ( 23001997) Crohn's disease ( 23128233) Dengue shock syndrome ( 22001756) Hodgkin's lymphoma ( 22286212) Metabolic syndrome ( 22399527) Pulmonary function ( 21946350)
Protein-Protein Interactions		4 interactors: MICB RAE1 TYROBP ULBP1	2 interactors: KLRC4 KLRK1
Entrez ID		8302	4277
HPRD ID		16008	03894
Ensembl ID		ENSG00000183542	ENSG00000204516
Uniprot IDs		O43908	A2AC57 F5H7Q8 Q29980 Q861E6
PDB IDs			1JE6 2WY3
Enriched GO Terms of Interacting Partners?		Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Leukocyte Activation Cell Activation Innate Immune Response Regulation Of Immune Response Immune Response Regulation Of Immune System Process Defense Response Leukocyte Mediated Immunity Antigen Processing And Presentation Regulation Of Osteoclast Development Gamma-delta T Cell Activation Neutrophil Activation Involved In Immune Response Negative Regulation Of Defense Response To Virus By Host Lymphocyte Activation Macrophage Activation Involved In Immune Response T Cell Mediated Cytotoxicity Immune System Process Viral Process Neutrophil Activation Cytolysis Negative Regulation Of Defense Response To Virus Macrophage Activation Regulation Of Defense Response To Virus By Host T Cell Mediated Immunity Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Cell Surface Receptor Signaling Pathway Cellular Defense Response Natural Killer Cell Activation Response To Stress Nuclear Envelope Organization MRNA Export From Nucleus Regulation Of Osteoclast Differentiation Glucose Transport RNA Export From Nucleus Hexose Transport Regulation Of Defense Response To Virus Response To Stimulus	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Defense Response Cellular Defense Response Natural Killer Cell Activation T Cell Costimulation Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Innate Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Response To Stress Regulation Of T Cell Activation Positive Regulation Of Cell Activation
Tagcloud ?			aberrantly allogeneic autologous axis bcsc bcscs cytotoxicity downregulation elusive escape failed infiltrating killer killing limit metastasis mica mir20a nk nkg2d oncogenic promoted restored resultant rich sensitized stimulatory thereby trans
Tagcloud (Difference) ?			aberrantly allogeneic autologous axis bcsc bcscs cytotoxicity downregulation elusive escape failed infiltrating killer killing limit metastasis mica mir20a nk nkg2d oncogenic promoted restored resultant rich sensitized stimulatory thereby trans
Tagcloud (Intersection) ?