MSMO1 and MARCHF6

Number of citations of the paper that reports this interaction (PubMedID 36958722)
57

Data Source:
BioGRID (protein complementation assay)

		MSMO1	MARCHF6
Description		methylsterol monooxygenase 1	membrane associated ring-CH-type finger 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	ER Ubiquitin Ligase Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	C-4 Methylsterol Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Enzyme Binding Ubiquitin Conjugating Enzyme Binding Metal Ion Binding Ubiquitin Protein Ligase Activity Ubiquitin-specific Protease Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Biosynthetic Process Sterol Biosynthetic Process	Cholesterol Biosynthetic Process Proteasomal Protein Catabolic Process Protein Ubiquitination ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cholesterol Biosynthetic Process Protein K48-linked Ubiquitination Endoplasmic Reticulum Mannose Trimming
Pathways		Cholesterol biosynthesis Cholesterol biosynthesis via lathosterol	ER Quality Control Compartment (ERQC)
Drugs		NADH
Diseases
GWAS		Heel bone mineral density ( 30598549) Neuroticism ( 27067015)
Interacting Genes		19 interacting genes: ATXN1 CHRM5 CYP4F22 DNAJC30 ERG28 GOLT1A GPR35 HMOX1 MARCHF6 MMP14 STRIT1 STX3 TMEM11 TMEM140 TMEM242 TMEM65 TMEM86B VKORC1 YIF1A	12 interacting genes: ADGRE2 BUD31 DIO2 MSMO1 MTNR1B RGS2 SQLE UBC UBE2D2 UBE2G1 UBE2G2 UBE2J2
Entrez ID		6307	10299
HPRD ID		07396	11095
Ensembl ID		ENSG00000052802	ENSG00000145495
Uniprot IDs		Q15800	O60337
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Ubiquitin Conjugating Enzyme Activity Ubiquitin Protein Ligase Binding Protein Ubiquitination Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Protein Polyubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Cholesterol Biosynthetic Process Post-translational Protein Modification ATP Binding Sterol Biosynthetic Process Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Squalene Monooxygenase Activity Ubiquitin-dependent Protein Catabolic Process Endoplasmic Reticulum Membrane Macromolecule Catabolic Process Ubiquitin-protein Transferase Activity Nucleotide Binding Negative Regulation Of Glycine Import Across Plasma Membrane Proteolysis Thyroxine 5'-deiodinase Activity Thyroxine 5-deiodinase Activity Thyroid Hormone Catabolic Process Steroid Biosynthetic Process C-4 Methylsterol Oxidase Activity Response To Biphenyl Catabolic Process ERAD Pathway Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Adenylate Cyclase Inhibitor Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?