MSMO1 and TMEM65

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSMO1	TMEM65
Description		methylsterol monooxygenase 1	transmembrane protein 65
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Nucleolus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Intercalated Disc Membrane
	Molecular Function	C-4 Methylsterol Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Biosynthetic Process Sterol Biosynthetic Process	Cardiac Ventricle Development Cardiac Conduction Regulation Of Cardiac Conduction
Pathways		Cholesterol biosynthesis Cholesterol biosynthesis via lathosterol
Drugs		NADH
Diseases
GWAS		Heel bone mineral density ( 30598549) Neuroticism ( 27067015)	Fear of minor pain ( 28701861)
Interacting Genes		19 interacting genes: ATXN1 CHRM5 CYP4F22 DNAJC30 ERG28 GOLT1A GPR35 HMOX1 MARCHF6 MMP14 STRIT1 STX3 TMEM11 TMEM140 TMEM242 TMEM65 TMEM86B VKORC1 YIF1A	33 interacting genes: ABHD16A AQP6 ARL13B CYB561 CYBRD1 EBP ERGIC3 FAM174A FAM209A GJA8 GPR42 HSD17B11 IGSF9 IL3RA JAGN1 JPH1 LMNA MSMO1 PDZK1IP1 PTGES PVR REEP4 RETREG3 SCN3B SLC10A6 SLC18A1 SLC35H1 SLC7A8 TIMMDC1 TMEM101 TMEM80 TMX2 ZFYVE27
Entrez ID		6307	157378
HPRD ID		07396	14102
Ensembl ID		ENSG00000052802	ENSG00000164983
Uniprot IDs		Q15800	Q6PI78
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Ascorbate Homeostasis Transmembrane Monodehydroascorbate Reductase Activity Endoplasmic Reticulum Transmembrane Transport Protein Binding
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