MSMO1 and TMEM140

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MSMO1	TMEM140
Description		methylsterol monooxygenase 1	transmembrane protein 140
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Membrane
	Molecular Function	C-4 Methylsterol Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Steroid Biosynthetic Process Cholesterol Biosynthetic Process Steroid Metabolic Process Cholesterol Metabolic Process Lipid Biosynthetic Process Sterol Biosynthetic Process
Pathways		Cholesterol biosynthesis Cholesterol biosynthesis via lathosterol
Drugs		NADH
Diseases
GWAS		Heel bone mineral density ( 30598549) Neuroticism ( 27067015)
Interacting Genes		19 interacting genes: ATXN1 CHRM5 CYP4F22 DNAJC30 ERG28 GOLT1A GPR35 HMOX1 MARCHF6 MMP14 STRIT1 STX3 TMEM11 TMEM140 TMEM242 TMEM65 TMEM86B VKORC1 YIF1A	51 interacting genes: APH1A AQP6 ASGR2 CD22 CD53 CD79A CGRRF1 CLDN5 CLDN7 CLEC17A CLRN1 CREB3 EBP ERGIC3 FAM209A FAM210B FCER1G FNDC9 GOLM1 GPR152 GPR42 HHLA2 HSD17B13 IFNGR2 KCNJ8 KRTAP10-8 LMNA LY6E MFF MGST3 MILR1 MS4A3 MSMO1 PDZK1IP1 PSCA RMDN3 SCN3B SHISAL1 SIT1 SLC39A9 SPACA1 STOM SYNE4 TEX29 TMEM182 TMEM205 TMEM207 TMEM9 TMX2 TSPAN12 TSPO2
Entrez ID		6307	55281
HPRD ID		07396	07723
Ensembl ID		ENSG00000052802	ENSG00000146859
Uniprot IDs		Q15800	Q9NV12
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane	Membrane Protein Binding External Side Of Plasma Membrane Plasma Membrane Identical Protein Binding Fucose Binding
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