HULC and LDHA

Number of citations of the paper that reports this interaction (PubMedID 32572027)
51

Data Source:
BioGRID (unspecified method, unspecified method)

		HULC	LDHA
Description		hepatocellular carcinoma up-regulated long non-coding RNA	lactate dehydrogenase A
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Mitochondrion Cytosol Membrane Sperm Fibrous Sheath Extracellular Exosome Oxidoreductase Complex
	Molecular Function		Catalytic Activity Lactate Dehydrogenase Activity L-lactate Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Identical Protein Binding Cadherin Binding
	Biological Process		Lactate Metabolic Process Glycolytic Process Glucose Catabolic Process To Lactate Via Pyruvate Carboxylic Acid Metabolic Process Substantia Nigra Development Pyruvate Catabolic Process
Pathways			Pyruvate metabolism Regulation of pyruvate metabolism
Drugs			NADH Etheno-NAD Nicotinamide Oxamic Acid Stiripentol Copper Artenimol
Diseases
GWAS			Amyloid A serum levels ( 21124955) Serum metabolite levels ( 33031748)
Interacting Genes		3 interacting genes: FGFR1 LDHA PKM	21 interacting genes: ABCC9 ACD CEBPA DUX4 DYNLL1 FGFR1 GSK3A HNRNPD HULC KCNJ11 MAPK10 NDRG1 PCNA POT1 PTPRF SRPK2 TERF1 TINF2 UPF2 XRN1 YWHAQ
Entrez ID		728655	3939
HPRD ID			01025
Ensembl ID		ENSG00000285219	ENSG00000134333
Uniprot IDs			P00338 V9HWB9
PDB IDs			1I10 4AJP 4JNK 4L4R 4L4S 4M49 4OJN 4OKN 4QO7 4QO8 4QSM 4QT0 4R68 4R69 4RLS 4ZVV 5IXS 5IXY 5W8H 5W8I 5W8J 5W8K 5W8L 5ZJD 5ZJE 5ZJF 6BAD 6BAG 6BAX 6BAZ 6BB0 6BB1 6BB2 6BB3 6MV8 6MVA 6Q0D 6Q13 6SBU 6SBV 6ZZR 7M2N 8FW6 9BK2 9BK3
Enriched GO Terms of Interacting Partners?		ADP Catabolic Process ADP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Glycolytic Process Glucose Catabolic Process Ribonucleoside Diphosphate Catabolic Process Pyruvate Metabolic Process Organic Acid Metabolic Process Purine Ribonucleotide Catabolic Process Ribonucleoside Diphosphate Metabolic Process Purine Nucleotide Catabolic Process Nucleoside Diphosphate Metabolic Process Nucleotide Catabolic Process Nicotinamide Nucleotide Metabolic Process Carbohydrate Catabolic Process Positive Regulation Of Mitotic Cell Cycle DNA Replication Protein Tyrosine Kinase Activity Positive Regulation Of Parathyroid Hormone Secretion Glucose Metabolic Process Nucleoside Phosphate Catabolic Process ATP Metabolic Process Hexose Metabolic Process Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Regulation Of Lateral Mesodermal Cell Fate Specification Monosaccharide Metabolic Process Carbohydrate Derivative Catabolic Process Organophosphate Catabolic Process Pyruvate Kinase Activity Ventricular Zone Neuroblast Division Regulation Of Mitotic Cell Cycle DNA Replication Phosphate-containing Compound Metabolic Process Orbitofrontal Cortex Development Lactate Dehydrogenase Activity Glucose Catabolic Process To Lactate Via Pyruvate Histone H3T11 Kinase Activity Small Molecule Metabolic Process Receptor-receptor Interaction Diphosphate Metabolic Process Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling Negative Regulation Of Fibroblast Growth Factor Production Positive Regulation Of Phospholipase Activity L-lactate Dehydrogenase (NAD+) Activity Purine Ribonucleotide Metabolic Process Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Activity Forebrain Neuroblast Division Ribonucleotide Metabolic Process Vitamin D3 Metabolic Process Cementum Mineralization	Telomeric DNA Binding Regulation Of DNA Biosynthetic Process Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Via Telomerase Shelterin Complex Nuclear Telomere Cap Complex Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Telomere Capping Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Chromosome Organization Telomere Maintenance Positive Regulation Of Chromosome Organization Negative Regulation Of Biosynthetic Process Regulation Of Chromosome Organization Telomere Organization Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Chromosome, Telomeric Region Response To Metal Ion Telomere Maintenance Via Telomerase Negative Regulation Of Metabolic Process Protein-containing Complex Binding RNA-templated DNA Biosynthetic Process DNA Biosynthetic Process Nucleic Acid Metabolic Process Telomere Maintenance Via Telomere Lengthening Macromolecule Metabolic Process Liver Development Inward Rectifying Potassium Channel Nucleobase-containing Compound Metabolic Process Regulation Of DNA Replication Regeneration ATP-activated Inward Rectifier Potassium Channel Activity Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of DNA Biosynthetic Process Response To Xenobiotic Stimulus Positive Regulation Of Organelle Organization Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere
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