TSPAN7 and BTG3

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		TSPAN7	BTG3
Description		tetraspanin 7	BTG anti-proliferation factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Negative Regulation Of Cell Population Proliferation Negative Regulation Of Mitotic Cell Cycle
Pathways		Cell surface interactions at the vascular wall Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS		White blood cell count ( 32888494)	Corpus callosum central volume ( 31530798) Feeling hurt ( 29500382)
Interacting Genes		27 interacting genes: ADRB2 BBS1 BTG3 BUD31 CACNA1A CCR2 CCR9 CHRM2 CHRM4 CREB3 DRD2 FAM209A FYTTD1 GNRHR GPR152 GPR35 GRIA2 GRIA3 HTR4 ITGB1 LHFPL5 LMNA LTB4R2 MEOX2 OXTR PICK1 SMO	76 interacting genes: ADNP2 AFF4 AGAP2 AHCYL1 AIP ATXN1 BANP CACNA1A CCDC13 CCT7 CLTC CLU CNOT7 CNOT8 CNTN4 COPS5 CREBZF CRYL1 DCLK2 DDX18 DIS3L DMAP1 DNAJC14 DNAJC7 DYNC1H1 EIF3C EIF3F EPRS1 GLUL HECTD2 HECTD4 HIVEP2 HSP90AA1 HSP90AB1 KCNQ2 KDM3A KIF3A MAPK8IP3 MORF4L1 MRPL38 MTM1 MYCBP2 NISCH NRBP1 OGT OSBPL8 OTOF PAK1 PAX6 PLA2G3 PLEKHB1 PPP2R5E PPP3CA PRKAR1A QARS1 RANBP9 RBL2 RNF10 RSPH1 SEC23IP SETDB1 SMG5 SPARCL1 SRPK2 SYNE1 TAF1 TAF6 TRIM32 TSC2 TSPAN7 USP8 WAPL WDFY3 XPC ZNF532 ZNF592
Entrez ID		7102	10950
HPRD ID		02107	10415
Ensembl ID		ENSG00000156298	ENSG00000154640
Uniprot IDs		P41732	Q14201 Q6IAU3
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Modulation Of Chemical Synaptic Transmission Anatomical Structure Homeostasis Tissue Homeostasis Regulation Of Biological Quality Chemical Synaptic Transmission Plasma Membrane Trans-synaptic Signaling Synaptic Signaling Cell-cell Signaling Signaling Endocytic Vesicle Membrane Cell Communication Dendrite Chemokine Receptor Activity Multicellular Organismal-level Homeostasis Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Amyloid-beta Binding Positive Regulation Of Neuroblast Proliferation Ionotropic Glutamate Receptor Signaling Pathway Neural Precursor Cell Proliferation G Protein-coupled Acetylcholine Receptor Activity Regulation Of Locomotion Postsynaptic Membrane Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Membrane Positive Regulation Of Neurotransmitter Uptake AMPA Glutamate Receptor Activity Ligand-gated Ion Channel Signaling Pathway Regulation Of Neuroblast Proliferation Neuroblast Proliferation Signal Transduction Patched Binding Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Cellular Defense Response Glutamate Receptor Signaling Pathway Synapse Positive Regulation Of Neural Precursor Cell Proliferation Ciliary Membrane G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Dendritic Spine Positive Regulation Of Cytosolic Calcium Ion Concentration Glutamate-gated Receptor Activity Negative Regulation Of Adenylate Cyclase Activity Cell Surface Receptor Signaling Pathway Regulation Of Multicellular Organism Growth Regulation Of Cell Motility Regulation Of System Process Cilium	Cytosol Cytoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Establishment Of Localization In Cell Regulation Of Macromolecule Biosynthetic Process Eukaryotic Translation Initiation Factor 3 Complex Organelle Organization Nucleus Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Metabolic Process RNA Binding Cytoskeleton Organization Chaperone-mediated Protein Complex Assembly Protein Localization To Organelle Translation Initiation Factor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Unfolded Protein Binding Regulation Of Gene Expression Translation Intracellular Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Intracellular Protein Localization Disordered Domain Specific Binding Regulation Of Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Telomerase Holoenzyme Complex Assembly Negative Regulation Of Catabolic Process CCR4-NOT Core Complex Chromatin Organization 3'-5'-RNA Exonuclease Activity Positive Regulation Of Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Gene Expression Nucleoplasm Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding ATP-dependent Protein Folding Chaperone
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