BTG3 and AIP

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		BTG3	AIP
Description		BTG anti-proliferation factor 3	AHR interacting HSP90 co-chaperone
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Aryl Hydrocarbon Receptor Complex
	Molecular Function	Protein Binding	Transcription Coregulator Activity Transcription Coactivator Activity Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Aryl Hydrocarbon Receptor Binding GAF Domain Binding Unfolded Protein Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Mitotic Cell Cycle	Protein Targeting To Mitochondrion Xenobiotic Metabolic Process Positive Regulation Of DNA-templated Transcription Protein Maturation
Pathways			Aryl hydrocarbon receptor signalling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Corpus callosum central volume ( 31530798) Feeling hurt ( 29500382)	Apolipoprotein A1 levels ( 32203549) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278) Urate levels ( 31578528)
Interacting Genes		76 interacting genes: ADNP2 AFF4 AGAP2 AHCYL1 AIP ATXN1 BANP CACNA1A CCDC13 CCT7 CLTC CLU CNOT7 CNOT8 CNTN4 COPS5 CREBZF CRYL1 DCLK2 DDX18 DIS3L DMAP1 DNAJC14 DNAJC7 DYNC1H1 EIF3C EIF3F EPRS1 GLUL HECTD2 HECTD4 HIVEP2 HSP90AA1 HSP90AB1 KCNQ2 KDM3A KIF3A MAPK8IP3 MORF4L1 MRPL38 MTM1 MYCBP2 NISCH NRBP1 OGT OSBPL8 OTOF PAK1 PAX6 PLA2G3 PLEKHB1 PPP2R5E PPP3CA PRKAR1A QARS1 RANBP9 RBL2 RNF10 RSPH1 SEC23IP SETDB1 SMG5 SPARCL1 SRPK2 SYNE1 TAF1 TAF6 TRIM32 TSC2 TSPAN7 USP8 WAPL WDFY3 XPC ZNF532 ZNF592	22 interacting genes: AHR ARNT BTG3 CEBPA CLEC7A CSNK2A1 EGFR ERBB2 GNA13 GNAQ HSP90AA1 HTR6 HUNK IKBKG IRF7 LCOR PDE4A PPARA PTGES3 STIP1 TNNI3K TOMM20
Entrez ID		10950	9049
HPRD ID		10415	10408
Ensembl ID		ENSG00000154640	ENSG00000110711
Uniprot IDs		Q14201 Q6IAU3	A0A804HJ38 A0A804HKL7 O00170
PDB IDs			2LKN 4AIF 4APO 7ZUB 8QMO
Enriched GO Terms of Interacting Partners?		Cytosol Cytoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Establishment Of Localization In Cell Regulation Of Macromolecule Biosynthetic Process Eukaryotic Translation Initiation Factor 3 Complex Organelle Organization Nucleus Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Metabolic Process RNA Binding Cytoskeleton Organization Chaperone-mediated Protein Complex Assembly Protein Localization To Organelle Translation Initiation Factor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Unfolded Protein Binding Regulation Of Gene Expression Translation Intracellular Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Intracellular Protein Localization Disordered Domain Specific Binding Regulation Of Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Telomerase Holoenzyme Complex Assembly Negative Regulation Of Catabolic Process CCR4-NOT Core Complex Chromatin Organization 3'-5'-RNA Exonuclease Activity Positive Regulation Of Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Gene Expression Nucleoplasm Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding ATP-dependent Protein Folding Chaperone	Hsp90 Protein Binding Nuclear Aryl Hydrocarbon Receptor Complex Signal Transduction Intracellular Signal Transduction Embryonic Placenta Development Protein Folding Chaperone Complex Telomerase Holoenzyme Complex Assembly Protein-containing Complex Nuclear Receptor Activity Aryl Hydrocarbon Receptor Complex Intestinal Epithelial Structure Maintenance ERBB2-EGFR Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Defense Response Positive Regulation Of Catabolic Process Protein Heterodimerization Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Nucleus Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Biosynthetic Process Intracellular Receptor Signaling Pathway Guanyl Nucleotide Binding Protein Stabilization Ruffle Membrane Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Protein Kinase Activity G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Signaling Pathway Chaperone-mediated Protein Complex Assembly Telomere Maintenance Via Telomerase DNA Polymerase Binding ERBB2 Signaling Pathway Positive Regulation Of Telomere Maintenance Via Telomerase Unfolded Protein Binding Regulation Of Multicellular Organismal Process Maintenance Of Gastrointestinal Epithelium Protein Import Into Mitochondrial Matrix Response To Xenobiotic Stimulus Regulation Of Intracellular Signal Transduction RNA-templated DNA Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Immune System Process Positive Regulation Of Signal Transduction Regulation Of Cell Population Proliferation
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