BTG3 and AGAP2

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		BTG3	AGAP2
Description		BTG anti-proliferation factor 3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Membrane Extracellular Exosome Flemming Body
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity GTPase Activator Activity Protein Binding ATP Binding GTP Binding Zinc Ion Binding Protein Kinase Binding Protein Kinase Activator Activity Phosphatidylinositol 3-kinase Regulator Activity Metal Ion Binding Phosphatidylinositol 3-kinase Activator Activity
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Mitotic Cell Cycle	Protein Transport Endosomal Transport Actin Cytoskeleton Organization Negative Regulation Of Protein Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Protein Kinase Activity
Pathways			Netrin-1 signaling
Drugs
Diseases
GWAS		Corpus callosum central volume ( 31530798) Feeling hurt ( 29500382)	Heel bone mineral density ( 30598549) Multiple sclerosis ( 21833088)
Interacting Genes		76 interacting genes: ADNP2 AFF4 AGAP2 AHCYL1 AIP ATXN1 BANP CACNA1A CCDC13 CCT7 CLTC CLU CNOT7 CNOT8 CNTN4 COPS5 CREBZF CRYL1 DCLK2 DDX18 DIS3L DMAP1 DNAJC14 DNAJC7 DYNC1H1 EIF3C EIF3F EPRS1 GLUL HECTD2 HECTD4 HIVEP2 HSP90AA1 HSP90AB1 KCNQ2 KDM3A KIF3A MAPK8IP3 MORF4L1 MRPL38 MTM1 MYCBP2 NISCH NRBP1 OGT OSBPL8 OTOF PAK1 PAX6 PLA2G3 PLEKHB1 PPP2R5E PPP3CA PRKAR1A QARS1 RANBP9 RBL2 RNF10 RSPH1 SEC23IP SETDB1 SMG5 SPARCL1 SRPK2 SYNE1 TAF1 TAF6 TRIM32 TSC2 TSPAN7 USP8 WAPL WDFY3 XPC ZNF532 ZNF592	16 interacting genes: AKT1 ARF1 BTG3 CDC42 CDK4 EPB41L1 GRIP1 HOMER1 HOMER2 NF2 PIK3R1 PLCG1 PRKAA1 RAC1 RAC2 RHOA
Entrez ID		10950	116986
HPRD ID		10415	05687
Ensembl ID		ENSG00000154640	ENSG00000135439
Uniprot IDs		Q14201 Q6IAU3	Q99490
PDB IDs			2BMJ 2IWR 2RLO
Enriched GO Terms of Interacting Partners?		Cytosol Cytoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Establishment Of Localization In Cell Regulation Of Macromolecule Biosynthetic Process Eukaryotic Translation Initiation Factor 3 Complex Organelle Organization Nucleus Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Metabolic Process RNA Binding Cytoskeleton Organization Chaperone-mediated Protein Complex Assembly Protein Localization To Organelle Translation Initiation Factor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Unfolded Protein Binding Regulation Of Gene Expression Translation Intracellular Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Intracellular Protein Localization Disordered Domain Specific Binding Regulation Of Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Telomerase Holoenzyme Complex Assembly Negative Regulation Of Catabolic Process CCR4-NOT Core Complex Chromatin Organization 3'-5'-RNA Exonuclease Activity Positive Regulation Of Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Gene Expression Nucleoplasm Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding ATP-dependent Protein Folding Chaperone	Intracellular Signaling Cassette Intracellular Signal Transduction Lamellipodium Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Lamellipodium Assembly Regulation Of Transport Regulation Of Stress Fiber Assembly Positive Regulation Of Lamellipodium Organization Regulation Of Actin Filament-based Process Regulation Of Cell-substrate Adhesion Regulation Of Lamellipodium Assembly Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Cell Projection Organization Cytosol Membrane Invagination Regulation Of Actin Filament Organization Dendrite Regulation Of Lamellipodium Organization Positive Regulation Of Stress Fiber Assembly Cytoplasm Positive Regulation Of Cellular Component Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Cell Adhesion Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Vesicle-mediated Transport Regulation Of Organelle Organization Positive Regulation Of Cell Migration Regulation Of Cell Population Proliferation Positive Regulation Of Cell Motility Positive Regulation Of Cell Projection Organization Cell Projection Actin Cytoskeleton Organization Positive Regulation Of Locomotion Signal Transduction Regulation Of Supramolecular Fiber Organization Apical Part Of Cell Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Migration Actin Filament-based Process Regulation Of Leukocyte Migration Positive Regulation Of Immune System Process Postsynapse Regulation Of Cell Projection Assembly Regulation Of Cell Motility Ruffle Membrane G Protein-coupled Glutamate Receptor Binding Regulation Of Cellular Component Organization Protein Kinase Binding Regulation Of Locomotion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?