BTG3 and PLEKHB1

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		BTG3	PLEKHB1
Description		BTG anti-proliferation factor 3	pleckstrin homology domain containing B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Mitotic Cell Cycle	Phototransduction Regulation Of Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Corpus callosum central volume ( 31530798) Feeling hurt ( 29500382)	Dimensional psychopathology (Cognitive) ( 29496196) Glucose homeostasis traits ( 25524916) Hand grip strength ( 27325353) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		76 interacting genes: ADNP2 AFF4 AGAP2 AHCYL1 AIP ATXN1 BANP CACNA1A CCDC13 CCT7 CLTC CLU CNOT7 CNOT8 CNTN4 COPS5 CREBZF CRYL1 DCLK2 DDX18 DIS3L DMAP1 DNAJC14 DNAJC7 DYNC1H1 EIF3C EIF3F EPRS1 GLUL HECTD2 HECTD4 HIVEP2 HSP90AA1 HSP90AB1 KCNQ2 KDM3A KIF3A MAPK8IP3 MORF4L1 MRPL38 MTM1 MYCBP2 NISCH NRBP1 OGT OSBPL8 OTOF PAK1 PAX6 PLA2G3 PLEKHB1 PPP2R5E PPP3CA PRKAR1A QARS1 RANBP9 RBL2 RNF10 RSPH1 SEC23IP SETDB1 SMG5 SPARCL1 SRPK2 SYNE1 TAF1 TAF6 TRIM32 TSC2 TSPAN7 USP8 WAPL WDFY3 XPC ZNF532 ZNF592	18 interacting genes: ACVR1 ATXN1 BAG3 BMPR1B BTG3 C10orf55 CCR8 DSCR9 GLIS2 GNGT1 LCOR RAP1GDS1 RBM11 RUNX1 SMAD1 TGFBR1 VENTX ZDHHC17
Entrez ID		10950	58473
HPRD ID		10415	09630
Ensembl ID		ENSG00000154640	ENSG00000021300
Uniprot IDs		Q14201 Q6IAU3	Q9UF11
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytosol Cytoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Establishment Of Localization In Cell Regulation Of Macromolecule Biosynthetic Process Eukaryotic Translation Initiation Factor 3 Complex Organelle Organization Nucleus Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Metabolic Process RNA Binding Cytoskeleton Organization Chaperone-mediated Protein Complex Assembly Protein Localization To Organelle Translation Initiation Factor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Unfolded Protein Binding Regulation Of Gene Expression Translation Intracellular Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Intracellular Protein Localization Disordered Domain Specific Binding Regulation Of Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Telomerase Holoenzyme Complex Assembly Negative Regulation Of Catabolic Process CCR4-NOT Core Complex Chromatin Organization 3'-5'-RNA Exonuclease Activity Positive Regulation Of Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Gene Expression Nucleoplasm Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding ATP-dependent Protein Folding Chaperone	Transforming Growth Factor Beta Receptor Activity, Type I Transmembrane Receptor Protein Serine/threonine Kinase Activity Activin Receptor Complex Activin Receptor Activity, Type I SMAD Binding Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway BMP Receptor Activity Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Osteoblast Differentiation Activin Binding Regulation Of Cartilage Development BMP Signaling Pathway Striated Muscle Cell Apoptotic Process Cellular Response To Growth Factor Stimulus Pharyngeal System Development Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Muscle Cell Apoptotic Process I-SMAD Binding Positive Regulation Of Cell Differentiation Transforming Growth Factor Beta Binding Poly(U) RNA Binding Positive Regulation Of RNA Metabolic Process Response To Growth Factor Osteoblast Differentiation Positive Regulation Of Extracellular Matrix Organization Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Osteoblast Differentiation Activin Receptor Signaling Pathway Cellular Response To BMP Stimulus Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cartilage Development Regulation Of Extrinsic Apoptotic Signaling Pathway Pattern Specification Process Ventricular Septum Morphogenesis Regulation Of RNA Metabolic Process Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Bone Mineralization Cell Fate Commitment Positive Regulation Of Vasculature Development Regulation Of Cardiac Muscle Cell Proliferation DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Growth Factor Binding Endocardial Cushion Cell Fate Commitment CAAX-box Protein Maturation Perforant Pathway To Dendrate Granule Cell Synapse Cellular Developmental Process
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