BTG3 and PLA2G3

Number of citations of the paper that reports this interaction (PubMedID 35914814)
83

Data Source:
BioGRID (two hybrid)

		BTG3	PLA2G3
Description		BTG anti-proliferation factor 3	phospholipase A2 group III
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Extracellular Space Cytoplasm Endosome Centriole Cytoskeleton Plasma Membrane Membrane Recycling Endosome
	Molecular Function	Protein Binding	Phospholipase Activity Phospholipase A2 Activity Hydrolase Activity Metal Ion Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Mitotic Cell Cycle	Acrosome Assembly Production Of Molecular Mediator Involved In Inflammatory Response Lipid Metabolic Process Phospholipid Metabolic Process Phosphatidylserine Metabolic Process Sperm Axoneme Assembly Negative Regulation Of Gene Expression Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Neuron Projection Development Lipoxygenase Pathway Cell Projection Organization Positive Regulation Of Prostaglandin Biosynthetic Process Positive Regulation Of Prostaglandin Secretion Low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Remodeling Macrophage Activation Mast Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Cell Differentiation Phosphatidylethanolamine Metabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process Phosphatidic Acid Metabolic Process Phosphatidylinositol Metabolic Process Cell Development Cell Maturation Arachidonate Secretion Cilium Assembly Positive Regulation Of Mast Cell Differentiation Positive Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Amyloid-beta Clearance Positive Regulation Of Histamine Secretion By Mast Cell Regulation Of Endocytic Recycling
Pathways			Acyl chain remodelling of PC Acyl chain remodelling of PE Acyl chain remodelling of PG
Drugs
Diseases
GWAS		Corpus callosum central volume ( 31530798) Feeling hurt ( 29500382)	Appendicular lean mass ( 33097823) Fish- and plant-related diet ( 32066663) Gut microbiota (beta diversity) ( 27723756) Oily fish consumption ( 32066663) Paclitaxel-induced neuropathy ( 23776197) Pork consumption ( 32066663)
Interacting Genes		76 interacting genes: ADNP2 AFF4 AGAP2 AHCYL1 AIP ATXN1 BANP CACNA1A CCDC13 CCT7 CLTC CLU CNOT7 CNOT8 CNTN4 COPS5 CREBZF CRYL1 DCLK2 DDX18 DIS3L DMAP1 DNAJC14 DNAJC7 DYNC1H1 EIF3C EIF3F EPRS1 GLUL HECTD2 HECTD4 HIVEP2 HSP90AA1 HSP90AB1 KCNQ2 KDM3A KIF3A MAPK8IP3 MORF4L1 MRPL38 MTM1 MYCBP2 NISCH NRBP1 OGT OSBPL8 OTOF PAK1 PAX6 PLA2G3 PLEKHB1 PPP2R5E PPP3CA PRKAR1A QARS1 RANBP9 RBL2 RNF10 RSPH1 SEC23IP SETDB1 SMG5 SPARCL1 SRPK2 SYNE1 TAF1 TAF6 TRIM32 TSC2 TSPAN7 USP8 WAPL WDFY3 XPC ZNF532 ZNF592	3 interacting genes: BTG3 PVR TGFB1I1
Entrez ID		10950	50487
HPRD ID		10415	07144
Ensembl ID		ENSG00000154640	ENSG00000100078
Uniprot IDs		Q14201 Q6IAU3	Q9NZ20
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytosol Cytoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Macromolecule Metabolic Process Establishment Of Localization In Cell Regulation Of Macromolecule Biosynthetic Process Eukaryotic Translation Initiation Factor 3 Complex Organelle Organization Nucleus Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Metabolic Process RNA Binding Cytoskeleton Organization Chaperone-mediated Protein Complex Assembly Protein Localization To Organelle Translation Initiation Factor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Unfolded Protein Binding Regulation Of Gene Expression Translation Intracellular Transport Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Amyloid Fibril Formation Intracellular Protein Localization Disordered Domain Specific Binding Regulation Of Cell Cycle Negative Regulation Of Protein Metabolic Process Regulation Of Protein Metabolic Process Telomerase Holoenzyme Complex Assembly Negative Regulation Of Catabolic Process CCR4-NOT Core Complex Chromatin Organization 3'-5'-RNA Exonuclease Activity Positive Regulation Of Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cellular Response To Insulin Stimulus Negative Regulation Of Gene Expression Nucleoplasm Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding ATP-dependent Protein Folding Chaperone	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Susceptibility To T Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Roundabout Binding Focal Adhesion Cell Adhesion Mediator Activity Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Immune Response To Tumor Cell Negative Regulation Of Cell Population Proliferation Nuclear Androgen Receptor Binding I-SMAD Binding Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Morphogenesis Of Embryonic Epithelium
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?