THRSP and BCAR3

Number of citations of the paper that reports this interaction (PubMedID 25640309)
0

Data Source:
BioGRID (two hybrid)

		THRSP	BCAR3
Description		thyroid hormone responsive	BCAR3 adaptor protein, NSP family member
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Focal Adhesion Membrane Anchoring Junction
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Molecular Function Inhibitor Activity	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding
	Biological Process	Lipid Metabolic Process Response To Bacterium Regulation Of Triglyceride Biosynthetic Process Regulation Of Lipid Biosynthetic Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Small GTPase-mediated Signal Transduction Positive Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Response To Xenobiotic Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Endothelin Receptor Signaling Pathway
Pathways		Carnitine shuttle MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Menarche (age at onset) ( 25231870) Tourette syndrome ( 30818990)	Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Liver fibrosis (total hepatic collagen content) ( 32953199) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)
Interacting Genes		25 interacting genes: AKT1 AURKA BAG4 BCAR3 BRMS1 ERBB2 FGFR4 FZR1 HMMR IGF1R INCA1 KRAS LSP1 PALB2 PARP1 PIK3CA PTPN1 RB1CC1 SMAD4 STK11 TEPSIN TGFB1 TSG101 WT1 ZMYND12	38 interacting genes: AGR3 AP1M1 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCDC57 CCL5 CST6 DKK3 DRC4 EGFR EPSTI1 ERBB2 ERBB3 ERBB4 ERRFI1 GAB1 GLCE GREB1 HOXC6 KIT KPNA1 MET MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP UBASH3A VPS45
Entrez ID		7069	8412
HPRD ID		03566	05268
Ensembl ID		ENSG00000151365	ENSG00000137936
Uniprot IDs		Q92748	A0A384MTS3 B3KNL6 B3KP06 O75815
PDB IDs			3T6A
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Cell Population Proliferation Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Signal Transduction Enzyme-linked Receptor Protein Signaling Pathway Carbohydrate Homeostasis Glucose Homeostasis Negative Regulation Of Apoptotic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Cell Communication Regulation Of Signaling Insulin Receptor Signaling Pathway Gland Development Cellular Response To Growth Factor Stimulus Apoptotic Process Response To Growth Factor Regulation Of Cellular Component Organization Positive Regulation Of Cell Population Proliferation Liver Development Programmed Cell Death Cell Death Anoikis Negative Regulation Of Cell Population Proliferation Protein-containing Complex Binding Protein Autophosphorylation Cell Surface Receptor Signaling Pathway Epithelial Cell Differentiation Regulation Of Cell Growth Positive Regulation Of Fibroblast Migration Regulation Of Growth Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Glucose Stimulus Regulation Of Protein Modification Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Regulation Of Protein Localization Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Carbohydrate Stimulus ERBB Signaling Pathway Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Catalytic Activity Cell Population Proliferation	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Activity ERBB2 Signaling Pathway Receptor Complex Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Basal Plasma Membrane Protein Tyrosine Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Epithelial Cell Proliferation Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Epithelial Cell Proliferation ERBB3:ERBB2 Complex Response To Epidermal Growth Factor Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Epidermal Growth Factor Receptor Activity Neuregulin Receptor Activity Regulation Of Cell Population Proliferation Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Epithelial Cell Proliferation Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Molecular Function Inhibitor Activity Positive Regulation Of Phosphate Metabolic Process Response To Growth Factor Regulation Of Protein Modification Process Protein Kinase Activity Positive Regulation Of Lymphocyte Migration Positive Chemotaxis ERBB2-EGFR Signaling Pathway Growth Factor Binding Regulation Of Primary Metabolic Process Cell Population Proliferation Positive Regulation Of Protein Phosphorylation Positive Regulation Of Receptor Signaling Pathway Via STAT ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Basolateral Plasma Membrane Positive Regulation Of Cell Migration Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway
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