THRSP and HMMR

Number of citations: 0 (PubMedID 25640309)
Data Source: BioGRID (two hybrid)

		THRSP	HMMR
Name		thyroid hormone responsive	hyaluronan mediated motility receptor
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Cell Surface Microtubule Cytoskeleton Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity Molecular Function Inhibitor Activity	Protein Binding Hyaluronic Acid Binding Cargo Receptor Activity
	Biological Process	Lipid Metabolic Process Response To Bacterium Regulation Of Triglyceride Biosynthetic Process Regulation Of Lipid Biosynthetic Process	Receptor-mediated Endocytosis Hyaluronan Catabolic Process
Pathways		Carnitine shuttle MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis	Hyaluronan metabolism Hyaluronan degradation AURKA Activation by TPX2
Drugs		None	Hyaluronic acid
GWAS		Menarche (age at onset) ( 25231870 ) Tourette syndrome ( 30818990 )	Metabolite levels ( 23823483 )
Novel Interactors		1 novel interactors: SLAMF7	None recorded
Interacting Genes		25 interacting genes: AKT1 AURKA BAG4 BCAR3 BRMS1 ERBB2 FGFR4 FZR1 HMMR IGF1R INCA1 KRAS LSP1 PALB2 PARP1 PIK3CA PTPN1 RB1CC1 SMAD4 STK11 TEPSIN TGFB1 TSG101 WT1 ZMYND12	18 interacting genes: ACTB BACH1 CALM1 CD44 CDH13 CEBPA CFTR GREB1 IL24 ITIH5 MAPK3 MORN4 NAT2 SVIL THRSP TPX2 TRIM54 TUBB2A
Entrez ID		7069	3161
HPRD ID		03566	02963
Ensembl ID		ENSG00000151365	ENSG00000072571
Uniprot IDs		Q92748	O75330
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Cell Population Proliferation Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Signal Transduction Enzyme-linked Receptor Protein Signaling Pathway Carbohydrate Homeostasis Glucose Homeostasis Negative Regulation Of Apoptotic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Regulation Of Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Cell Communication Regulation Of Signaling Insulin Receptor Signaling Pathway Gland Development Cellular Response To Growth Factor Stimulus Apoptotic Process Response To Growth Factor Regulation Of Cellular Component Organization Positive Regulation Of Cell Population Proliferation Liver Development Programmed Cell Death Cell Death Anoikis Negative Regulation Of Cell Population Proliferation Protein-containing Complex Binding Protein Autophosphorylation Cell Surface Receptor Signaling Pathway Epithelial Cell Differentiation Regulation Of Cell Growth Positive Regulation Of Fibroblast Migration Regulation Of Growth Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Glucose Stimulus Regulation Of Protein Modification Process Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Regulation Of Protein Localization Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Cellular Response To Carbohydrate Stimulus ERBB Signaling Pathway Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Catalytic Activity Cell Population Proliferation	Focal Adhesion Negative Regulation Of Protein-containing Complex Disassembly Regulation Of Protein Depolymerization Calyx Of Held