SULT4A1 and PTPA

Number of citations of the paper that reports this interaction (PubMedID 20920535)
0

Data Source:
BioGRID (enzymatic study)

		SULT4A1	PTPA
Description		sulfotransferase family 4A member 1	protein phosphatase 2 phosphatase activator
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Exosome ATPase Complex
	Molecular Function	Protein Binding Sulfotransferase Activity Transferase Activity Identical Protein Binding	Nucleotide Binding Peptidyl-prolyl Cis-trans Isomerase Activity Phosphoprotein Phosphatase Activity Signaling Receptor Binding Protein Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity Isomerase Activity Phosphatase Activator Activity Protein Phosphatase Regulator Activity Phosphatase Binding Protein Homodimerization Activity Metal Ion Binding Protein Phosphatase 2A Binding
	Biological Process	Lipid Metabolic Process Sulfur Compound Metabolic Process Steroid Metabolic Process Sulfation Dendrite Arborization	Mitotic Spindle Organization Positive Regulation Of Apoptotic Process
Pathways		Cytosolic sulfonation of small molecules
Drugs
Diseases
GWAS		Type 2 diabetes (dietary heme iron intake interaction) ( 23386860)
Interacting Genes		6 interacting genes: AKT1 MAPK3 POT1 PTPA RUNX1 TGM1	32 interacting genes: AKT1 AMOT APP AURKB CCDC125 CCNE1 CCNG1 CCNG2 CSNK2A1 CYLD DTD1 EIF4EBP1 F3 FOXO3 GRIN3A GSK3B H2AX HDAC4 KISS1R MAPT MID1 NIF3L1 PPP2R1A PPP2R3A PRKCB RACGAP1 SGO1 SPG21 SRC SULT4A1 TEP1 TERT
Entrez ID		25830	5524
HPRD ID		07462	02858
Ensembl ID		ENSG00000130540	ENSG00000119383
Uniprot IDs		B7Z2E1 Q9BR01	F6WIT2 Q15257
PDB IDs		1ZD1	2G62 2HV6 2HV7 2IXM 4LAC 4NY3
Enriched GO Terms of Interacting Partners?		Cellular Response To Amino Acid Starvation Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of T Cell Activation Negative Regulation Of Cell-cell Adhesion Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of TORC1 Signaling Regulation Of Proteolysis Negative Regulation Of Cell Adhesion Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of DNA Metabolic Process Response To Amino Acid Starvation Negative Regulation Of Leukocyte Cell-cell Adhesion Negative Regulation Of Lipid Transport Response To Epidermal Growth Factor TORC1 Signaling Regulation Of Protein Maturation Lipopolysaccharide-mediated Signaling Pathway Phosphatase Binding Positive Regulation Of Cellular Component Organization ERBB Signaling Pathway TOR Signaling Regulation Of TRNA Methylation Insulin Receptor Signaling Pathway Positive Regulation Of Telomere Maintenance Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Regulation Of DNA Metabolic Process Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Positive Regulation Of Organelle Organization Regulation Of Organ Growth Cellular Response To Tumor Necrosis Factor Regulation Of Cell-cell Adhesion ATP Binding Negative Regulation Of Immune System Process Regulation Of Lymphocyte Activation Negative Regulation Of Autophagy Regulation Of Cellular Response To Stress Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Protein Autophosphorylation Response To Tumor Necrosis Factor Negative Regulation Of Protein Localization To Lysosome Cell Envelope Organization Positive Regulation Of Telomeric Loop Disassembly Positive Regulation Of Protein Localization To Endoplasmic Reticulum Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Insulin-like Growth Factor Stimulus Regulation Of Cell Activation	Regulation Of Cell Cycle Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling Intracellular Signal Transduction Positive Regulation Of Cell Communication Regulation Of Signal Transduction Positive Regulation Of Signaling Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Cytoplasm Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Communication Regulation Of Wnt Signaling Pathway TOR Signaling Positive Regulation Of Signal Transduction Regulation Of Apoptotic Signaling Pathway Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Phase Transition Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Protein Localization Response To Nerve Growth Factor Positive Regulation Of Cell Cycle Signal Transduction Regulation Of Mitotic Cell Cycle Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Mitotic Cell Cycle Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Canonical Wnt Signaling Pathway Enzyme Binding Mitotic Cell Cycle Phase Transition Negative Regulation Of Intracellular Signal Transduction Regulation Of TOR Signaling Regulation Of Protein Localization To Nucleus Regulation Of Developmental Process Negative Regulation Of Metabolic Process Regulation Of Cell Motility Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Wnt Signaling Pathway Protein Kinase Binding Regulation Of Locomotion Positive Regulation Of Developmental Process Positive Regulation Of TOR Signaling Mitochondrion Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Negative Regulation Of TOR Signaling Response To Growth Factor
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