TGFB1I1 and MAPK15

Number of citations of the paper that reports this interaction (PMID 16624805)
10

Data Source:
HPRD (in vivo)

		TGFB1I1	MAPK15
Gene Name		transforming growth factor beta 1 induced transcript 1	mitogen-activated protein kinase 15
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Cytoskeleton Focal Adhesion Nuclear Matrix Extracellular Matrix	Extracellular Region Intracellular Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding	MAP Kinase Activity ATP Binding SH3 Domain Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Cell Adhesion Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter MAPK Cascade Positive Regulation Of Protein Phosphorylation Negative Regulation Of DNA Replication Positive Regulation Of Protein Ubiquitination Response To Estradiol Positive Regulation Of Protein Catabolic Process Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		29 interactors: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL	8 interactors: CLIC3 CSK GABARAP GABARAPL1 MBP NR3C1 SRC TGFB1I1
Entrez ID		7041	225689
HPRD ID		03831	16867
Ensembl ID		ENSG00000140682	ENSG00000181085
Uniprot IDs		O43294	Q8TD08
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Regulation Of Signaling Regulation Of Cellular Protein Metabolic Process Cell Activation Positive Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Signaling Cell Communication Signal Transduction Response To Stimulus Regulation Of Catalytic Activity Transforming Growth Factor Beta Receptor Signaling Pathway Response To Organic Substance Organ Development Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Modification Process Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Cell Surface Receptor Signaling Pathway System Development Response To Transforming Growth Factor Beta Regulation Of Metabolic Process Positive Regulation Of Protein Catabolic Process Anatomical Structure Development Regulation Of Protein Catabolic Process Negative Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Negative Regulation Of Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Response To Growth Factor Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Negative Regulation Of Signaling Cellular Response To Stimulus Multicellular Organismal Development Regulation Of Cellular Process Positive Regulation Of Protein Kinase Activity Developmental Process Positive Regulation Of Kinase Activity Negative Regulation Of Transferase Activity Positive Regulation Of Protein Phosphorylation	Intracellular Steroid Hormone Receptor Signaling Pathway Cell Communication Morphogenesis Of An Epithelium Nucleophagy Intracellular Receptor Signaling Pathway Tissue Morphogenesis Mitochondrion Degradation Regulation Of Bone Resorption Organelle Disassembly Peptidyl-tyrosine Autophosphorylation Regulation Of Bone Remodeling Autophagic Vacuole Assembly Membrane Organization Response To Progesterone Response To Hormone Macroautophagy Mammary Gland Duct Morphogenesis Response To Stress Regulation Of Tissue Remodeling Response To Stimulus Response To Fatty Acid Epithelium Development Negative Regulation Of Signal Transduction Signaling T Cell Costimulation Response To Nutrient Levels Mammary Gland Morphogenesis Glucocorticoid Mediated Signaling Pathway Adherens Junction Organization Negative Regulation Of Signaling Response To Extracellular Stimulus Response To Steroid Hormone Mammary Gland Epithelium Development Regulation Of Glucose Metabolic Process Vacuole Organization Regulation Of Cytokine Production Cellular Response To Progesterone Stimulus Cellular Response To Hormone Stimulus Cellular Response To Stimulus Membrane Fusion Cellular Response To Starvation Defense Response To Nematode Negative Regulation Of Glucocorticoid Mediated Signaling Pathway Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Carbohydrate Metabolic Process Gland Morphogenesis Autophagy Epidermal Growth Factor Receptor Signaling Pathway Response To Corticosteroid ERBB Signaling Pathway
Tagcloud ?		aii aiii aiiis aiis astrocytoma astrocytomas beta1 bioinformatics biomarker contributing emt focused grade grades idh1 integration malignant microarrays multistep nbt progress progression qpcr shrna tp53 transcript transition validated	atypical autonomous autonomously biogenesis consequently coordinates delay dilp dilps drosophila effector epistatically erk7 erk8 humoral impede ipcs larval limiting neurosecretory nutrient nutrition operates ribosome secreting secretion starvation surveillance uncover
Tagcloud (Difference) ?		aii aiii aiiis aiis astrocytoma astrocytomas beta1 bioinformatics biomarker contributing emt focused grade grades idh1 integration malignant microarrays multistep nbt progress progression qpcr shrna tp53 transcript transition validated	atypical autonomous autonomously biogenesis consequently coordinates delay dilp dilps drosophila effector epistatically erk7 erk8 humoral impede ipcs larval limiting neurosecretory nutrient nutrition operates ribosome secreting secretion starvation surveillance uncover
Tagcloud (Intersection) ?