TGFB1I1 and PLA2G3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		TGFB1I1	PLA2G3
Gene Name		transforming growth factor beta 1 induced transcript 1	phospholipase A2, group III
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytoplasm Cytoskeleton Focal Adhesion Nuclear Matrix Extracellular Matrix	Extracellular Region Extracellular Space Centriole Plasma Membrane Mast Cell Granule
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding	Calcium Ion Binding Calcium-dependent Phospholipase A2 Activity
	Biological Process	Transcription From RNA Polymerase II Promoter Cell Adhesion Negative Regulation Of Cell Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated	Acrosome Assembly Phospholipid Metabolic Process Sperm Axoneme Assembly Lipid Catabolic Process Lipoxygenase Pathway Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Mast Cell Degranulation Small Molecule Metabolic Process Glycerophospholipid Biosynthetic Process Cilium Morphogenesis
Pathways			Acyl chain remodelling of PG Acyl chain remodelling of PE Metabolism of lipids and lipoproteins Phospholipid metabolism Glycerophospholipid biosynthesis Acyl chain remodelling of PC
Drugs
Diseases
GWAS			Paclitaxel-induced neuropathy ( 23776197)
Protein-Protein Interactions		29 interactors: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL	2 interactors: PVR TGFB1I1
Entrez ID		7041	50487
HPRD ID		03831	07144
Ensembl ID		ENSG00000140682	ENSG00000100078
Uniprot IDs		O43294	Q9NZ20
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Regulation Of Protein Phosphorylation Regulation Of Signal Transduction Regulation Of Phosphorus Metabolic Process Regulation Of Signaling Regulation Of Cellular Protein Metabolic Process Cell Activation Positive Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Signaling Cell Communication Signal Transduction Response To Stimulus Regulation Of Catalytic Activity Transforming Growth Factor Beta Receptor Signaling Pathway Response To Organic Substance Organ Development Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Modification Process Cellular Response To Organic Substance Cellular Response To Transforming Growth Factor Beta Stimulus Cell Surface Receptor Signaling Pathway System Development Response To Transforming Growth Factor Beta Regulation Of Metabolic Process Positive Regulation Of Protein Catabolic Process Anatomical Structure Development Regulation Of Protein Catabolic Process Negative Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus Negative Regulation Of Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Ubiquitination Response To Growth Factor Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Phosphorylation Response To Organic Cyclic Compound Negative Regulation Of Signaling Cellular Response To Stimulus Multicellular Organismal Development Regulation Of Cellular Process Positive Regulation Of Protein Kinase Activity Developmental Process Positive Regulation Of Kinase Activity Negative Regulation Of Transferase Activity Positive Regulation Of Protein Phosphorylation	Susceptibility To T Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Ubiquitin-dependent SMAD Protein Catabolic Process Positive Regulation Of Immune Response To Tumor Cell Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Adhesion Positive Regulation Of Epithelial To Mesenchymal Transition Androgen Receptor Signaling Pathway Viral Entry Into Host Cell Entry Into Host Cell Positive Regulation Of Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Fat Cell Differentiation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of T Cell Mediated Cytotoxicity Adherens Junction Organization Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Leukocyte Mediated Cytotoxicity Interaction With Host Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of T Cell Mediated Immunity Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Cell Killing Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Leukocyte Mediated Cytotoxicity Response To Heat Regulation Of Fat Cell Differentiation Positive Regulation Of Adaptive Immune Response Positive Regulation Of Cell Morphogenesis Involved In Differentiation Morphogenesis Of Embryonic Epithelium Positive Regulation Of Innate Immune Response Regulation Of Cellular Response To Growth Factor Stimulus Response To Temperature Stimulus Viral Life Cycle Regulation Of Adaptive Immune Response Intracellular Receptor Signaling Pathway Cell Junction Assembly Cell-cell Junction Organization
Tagcloud ?		aii aiii aiiis aiis astrocytoma astrocytomas beta1 bioinformatics biomarker contributing emt focused grade grades idh1 integration malignant microarrays multistep nbt progress progression qpcr shrna tp53 transcript transition validated
Tagcloud (Difference) ?		aii aiii aiiis aiis astrocytoma astrocytomas beta1 bioinformatics biomarker contributing emt focused grade grades idh1 integration malignant microarrays multistep nbt progress progression qpcr shrna tp53 transcript transition validated
Tagcloud (Intersection) ?