TFF1 and VSNL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TFF1	VSNL1
Description		trefoil factor 1	visinin like 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytosol Membrane
	Molecular Function	Protein Binding Growth Factor Activity	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Signal Transduction Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Response To Iron Ion Cell Differentiation Maintenance Of Gastrointestinal Epithelium Response To Immobilization Stress Response To Peptide Hormone	Regulation Of Signal Transduction Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion
Pathways		Estrogen-dependent gene expression
Drugs		Raloxifene Afimoxifene
Diseases
GWAS		Blood protein levels ( 30072576) Pancreatic cancer ( 22158540)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Energy expenditure ( 30071075) Psychosis and Alzheimer's disease ( 22005930) Response to fenofibrate (total cholesterol levels) ( 27002377) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		20 interacting genes: AKT1 APC ATM BTN3A1 BTNL8 CD300LD ESR2 FCRL4 FGFR2 GKN2 MUC6 RAD51 SGTB SIGLEC8 TSG101 UBQLN1 UBQLN4 VSNL1 XRCC3 ZNF250	18 interacting genes: ACTB ATXN1 C1QTNF2 CDSN CHRNA4 COL10A1 DTX2 ENDOD1 FAM131C GFI1B HUNK LITAF SPRED1 SPRED2 SPRY3 SRL TEX13B TFF1
Entrez ID		7031	7447
HPRD ID		00219	02890
Ensembl ID		ENSG00000160182	ENSG00000163032
Uniprot IDs		P04155	P62760
PDB IDs		1HI7 1PS2 6V1D
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Mitotic Sister Chromatid Separation Regulation Of Cell Cycle Phase Transition Proteolysis Involved In Protein Catabolic Process Regulation Of Macroautophagy Response To Alcohol Regulation Of Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Separation Regulation Of Double-strand Break Repair Via Homologous Recombination Telomere Maintenance ATP-dependent DNA Damage Sensor Activity Telomere Maintenance Via Recombination Mitotic Recombination Regulation Of Sister Chromatid Segregation Cellular Response To Stress Cellular Response To Decreased Oxygen Levels Protein Autophosphorylation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cellular Response To Stress Identical Protein Binding Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Chromosome Segregation Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Nuclear Division Regulation Of Mitotic Nuclear Division Response To X-ray Cellular Response To Gamma Radiation Regulation Of Double-strand Break Repair Recombinational Repair Autophagy Reciprocal Meiotic Recombination Telomere Organization Regulation Of DNA Recombination Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Immune Response-activating Signaling Pathway Cellular Response To Oxygen Levels Negative Regulation Of Macroautophagy Regulation Of Protein Catabolic Process Regulation Of Autophagy Macroautophagy Homologous Recombination Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Macromolecule Catabolic Process Regulation Of TRNA Methylation Negative Regulation Of Mitotic Nuclear Division Meiosis I	Negative Regulation Of Lens Fiber Cell Differentiation Stem Cell Factor Receptor Binding Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Nuclear Matrix Protein Serine/threonine Kinase Inhibitor Activity Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Negative Regulation Of Cornification Collagen Type X Trimer Negative Regulation Of MAPK Cascade Negative Regulation Of Neuron Projection Arborization Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Epithelial Cell Differentiation
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?