TFF1 and BTNL8

Number of citations of the paper that reports this interaction (PubMedID 21982860)
0

Data Source:
BioGRID (pull down)

		TFF1	BTNL8
Description		trefoil factor 1	butyrophilin like 8
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Growth Factor Activity	Signaling Receptor Binding Protein Binding
	Biological Process	Carbohydrate Metabolic Process Signal Transduction Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Response To Iron Ion Cell Differentiation Maintenance Of Gastrointestinal Epithelium Response To Immobilization Stress Response To Peptide Hormone	Regulation Of Cytokine Production Adaptive Immune Response Immune System Process T Cell Receptor Signaling Pathway
Pathways		Estrogen-dependent gene expression	Butyrophilin (BTN) family interactions
Drugs		Raloxifene Afimoxifene
Diseases
GWAS		Blood protein levels ( 30072576) Pancreatic cancer ( 22158540)	Blood protein levels ( 30072576)
Interacting Genes		20 interacting genes: AKT1 APC ATM BTN3A1 BTNL8 CD300LD ESR2 FCRL4 FGFR2 GKN2 MUC6 RAD51 SGTB SIGLEC8 TSG101 UBQLN1 UBQLN4 VSNL1 XRCC3 ZNF250	5 interacting genes: CLDN5 HHLA2 IFNGR2 MILR1 TFF1
Entrez ID		7031	79908
HPRD ID		00219	12549
Ensembl ID		ENSG00000160182	ENSG00000113303
Uniprot IDs		P04155	Q6UX41
PDB IDs		1HI7 1PS2 6V1D
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of Mitotic Sister Chromatid Separation Regulation Of Cell Cycle Phase Transition Proteolysis Involved In Protein Catabolic Process Regulation Of Macroautophagy Response To Alcohol Regulation Of Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Separation Regulation Of Double-strand Break Repair Via Homologous Recombination Telomere Maintenance ATP-dependent DNA Damage Sensor Activity Telomere Maintenance Via Recombination Mitotic Recombination Regulation Of Sister Chromatid Segregation Cellular Response To Stress Cellular Response To Decreased Oxygen Levels Protein Autophosphorylation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cellular Response To Stress Identical Protein Binding Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Chromosome Segregation Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Nuclear Division Regulation Of Mitotic Nuclear Division Response To X-ray Cellular Response To Gamma Radiation Regulation Of Double-strand Break Repair Recombinational Repair Autophagy Reciprocal Meiotic Recombination Telomere Organization Regulation Of DNA Recombination Double-strand Break Repair Via Homologous Recombination Negative Regulation Of Double-strand Break Repair Via Homologous Recombination Immune Response-activating Signaling Pathway Cellular Response To Oxygen Levels Negative Regulation Of Macroautophagy Regulation Of Protein Catabolic Process Regulation Of Autophagy Macroautophagy Homologous Recombination Polyubiquitin Modification-dependent Protein Binding Negative Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Macromolecule Catabolic Process Regulation Of TRNA Methylation Negative Regulation Of Mitotic Nuclear Division Meiosis I
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