VSNL1 and SRL

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		VSNL1	SRL
Name		visinin like 1	sarcalumenin
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen
	Molecular Function	Calcium Ion Binding Protein Binding Metal Ion Binding	Protein Binding GTP Binding
	Biological Process	Regulation Of Signal Transduction Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion	Store-operated Calcium Entry
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444 ) Energy expenditure ( 30071075 ) Psychosis and Alzheimer's disease ( 22005930 ) Response to fenofibrate (total cholesterol levels) ( 27002377 ) Squamous cell lung carcinoma ( 28604730 )	Blood protein levels ( 30072576 ) Brain morphology (MOSTest) ( 32665545 ) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098 ) Hip circumference adjusted for BMI ( 34021172 ) Hip index ( 34021172 ) Metabolite levels ( 23823483 ) Obesity-related traits ( 23251661 ) PR interval ( 32439900 ) QT interval ( 24952745 ) Serum alkaline phosphatase levels ( 33547301 )
Interacting Genes		18 interacting genes: ACTB ATXN1 C1QTNF2 CDSN CHRNA4 COL10A1 DTX2 ENDOD1 FAM131C GFI1B HUNK LITAF SPRED1 SPRED2 SPRY3 SRL TEX13B TFF1	3 interacting genes: KCNIP3 SGTA VSNL1
Entrez ID		7447	6345
HPRD ID		02890	19351
Ensembl ID		ENSG00000163032	ENSG00000185739
Uniprot IDs		P62760	B3KPP4 Q86TD4
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Negative Regulation Of Lens Fiber Cell Differentiation Stem Cell Factor Receptor Binding Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Nuclear Matrix Protein Serine/threonine Kinase Inhibitor Activity Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Negative Regulation Of Cornification Collagen Type X Trimer Negative Regulation Of MAPK Cascade Negative Regulation Of Neuron Projection Arborization Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Epithelial Cell Differentiation	None