TFDP1 and NPDC1

Number of citations of the paper that reports this interaction (PubMedID 11042687)
0

Data Source:
HPRD (in vitro)

		TFDP1	NPDC1
Description		transcription factor Dp-1	neural proliferation, differentiation and control 1
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Rb-E2F Complex RNA Polymerase II Transcription Regulator Complex	Plasma Membrane Membrane
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Domain Specific Binding DNA-binding Transcription Factor Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Epidermis Development Anoikis Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity Regulation Of Cell Cycle Negative Regulation Of Fat Cell Proliferation Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of DNA Biosynthetic Process
Pathways		Activation of NOXA and translocation to mitochondria Inhibition of replication initiation of damaged DNA by RB1/E2F1 Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by DREAM complex Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 Activation of PUMA and translocation to mitochondria G0 and Early G1 Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Oxidative Stress Induced Senescence Oncogene Induced Senescence TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest Cyclin E associated events during G1/S transition G1/S-Specific Transcription G1/S-Specific Transcription Cyclin D associated events in G1 Cyclin A:Cdk2-associated events at S phase entry Transcriptional Regulation by E2F6 Transcriptional regulation of granulopoiesis Transcriptional regulation of granulopoiesis Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Height ( 31562340) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Mild influenza (H1N1) infection ( 26379185)	Lymphocyte count ( 27863252) Monocyte percentage of white cells ( 27863252 32888494) White blood cell count ( 27863252 32888494)
Interacting Genes		20 interacting genes: CDK1 CDK2 CDK6 CDKN2A CREBBP CRYAA E2F1 E2F2 E2F3 E2F4 E2F5 E2F6 NPDC1 OGT SERTAD2 SIAH1 SOCS3 TP53 TP53BP1 UBC	41 interacting genes: C3orf52 CCND1 CCND2 CCND3 CDK2 CPT1A CYSRT1 E2F1 EMD FHL5 HINFP HNRNPK KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-12 KRTAP4-4 KRTAP5-9 KRTAP9-3 MADD MAL MDFI MS4A13 NBPF19 NOTCH2NLA PLSCR1 RBMY1F RBMY1J TFDP1
Entrez ID		7027	56654
HPRD ID		01792	12048
Ensembl ID		ENSG00000198176	ENSG00000107281
Uniprot IDs		Q14186	Q9NQX5
PDB IDs		2AZE 5GOW 5TUU 5TUV
Enriched GO Terms of Interacting Partners?		Transcription Regulator Complex Nucleoplasm RNA Polymerase II Transcription Regulator Complex DNA-binding Transcription Activator Activity Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Protein Dimerization Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Cell Cycle DNA Damage Checkpoint Signaling Positive Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Phase Transition Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Signal Transduction In Response To DNA Damage P53 Binding Regulation Of Gene Expression Nucleus Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Programmed Cell Death Positive Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process G1/S Transition Of Mitotic Cell Cycle Cis-regulatory Region Sequence-specific DNA Binding Cell Cycle G1/S Phase Transition Apoptotic Process Cyclin-dependent Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Cycle Phase Transition Programmed Cell Death Cell Death DNA-binding Transcription Factor Activity Negative Regulation Of Transcription By RNA Polymerase II Cyclin Binding Lens Fiber Cell Apoptotic Process Regulation Of DNA Replication Intracellular Signal Transduction Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Cell Cycle Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Negative Regulation Of Cell Cycle Process	Intermediate Filament Keratin Filament Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Cytosol Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Checkpoint Signaling Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Regulation Of MRNA Processing Anoikis Positive Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Hair Cycle Protein Serine/threonine Kinase Activator Activity Identical Protein Binding Mitotic G1 DNA Damage Checkpoint Signaling Mitotic G1/S Transition Checkpoint Signaling Regulation Of Cell Cycle Regulation Of RNA Splicing Positive Regulation Of Cell Cycle Regulation Of MRNA Metabolic Process Regulation Of Mitotic Cell Cycle Microtubule Organizing Center Response To X-ray Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Cell Cycle Phase Transition Liver Regeneration TMEM240-body Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane
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