NPDC1 and CCND2

Number of citations of the paper that reports this interaction (PMID 11042687)
2

Data Source:
HPRD (in vitro)

		NPDC1	CCND2
Gene Name		neural proliferation, differentiation and control, 1	cyclin D2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Cyclin-dependent Protein Kinase Holoenzyme Complex Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Nuclear Membrane
	Molecular Function		Protein Binding Protein Kinase Binding
	Biological Process		Positive Regulation Of Protein Phosphorylation Cell Cycle Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Division
Pathways			Cyclin D associated events in G1 G1 Phase Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Colorectal cancer ( 23266556 23263487) Major depressive disorder ( 19107115 23377640) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443) Red blood cell count ( 20139978) Red blood cell traits ( 23222517)
Protein-Protein Interactions		21 interactors: CCND1 CCND2 CCND3 CDK2 CPT1A E2F1 HINFP HNRNPK KHDRBS2 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-9 KRTAP4-12 KRTAP5-9 MADD MDFI NOTCH2NL PLSCR1 TFDP1	19 interactors: ABL1 AKAP8 CALM1 CALM2 CALM3 CDK4 CDK5 CDKN1A CDKN1B CDKN2A DMTF1 FBXL2 HIST1H1A NPDC1 PCGF2 PSMD10 RB1 RUNX1 SERTAD1
Entrez ID		56654	894
HPRD ID		12048	00451
Ensembl ID		ENSG00000107281	ENSG00000118971
Uniprot IDs		Q9NQX5	P30279
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Protein Serine/threonine Kinase Activity Notch Signaling Pathway DNA Damage Checkpoint Anoikis Positive Regulation Of Protein Kinase Activity Cell Cycle Positive Regulation Of Kinase Activity Cell Cycle Checkpoint Regulation Of Cell Cycle Regulation Of Metabolic Process Positive Regulation Of Transferase Activity Positive Regulation Of Cell Cycle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Process Positive Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Regulation Of Protein Kinase Activity Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Kinase Activity Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Transcription, DNA-templated Cell Division Positive Regulation Of Phosphorylation Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Gene Expression Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Catalytic Activity RNA Biosynthetic Process Cellular Response To Stimulus Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Cellular Response To Fatty Acid Regulation Of Transcription, DNA-templated Regulation Of Protein Phosphorylation	Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Regulation Of Cell Cycle Regulation Of Cell Cycle Process Regulation Of Protein Phosphorylation Negative Regulation Of Phosphorylation Regulation Of Phosphorylation Negative Regulation Of Protein Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Arrest Positive Regulation Of Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Regulation Of Cellular Localization Positive Regulation Of Cell Cycle Regulation Of Cellular Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Response To Corticosterone Cell Cycle Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Catalytic Activity Positive Regulation Of Cell Cycle Process Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mitotic Cell Cycle Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Mineralocorticoid Positive Regulation Of Oxidoreductase Activity Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Fc Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transferase Activity Cell Cycle Arrest Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Response To Organic Cyclic Compound Detection Of Calcium Ion
Tagcloud ?			associations blotting ccnd1 dab2 dact1 day detect displayed expressions fosl1 increasing jun mean pathway pcr placenta play promoting real relationship signaling spss target tissue tissues trend value western wnt
Tagcloud (Difference) ?			associations blotting ccnd1 dab2 dact1 day detect displayed expressions fosl1 increasing jun mean pathway pcr placenta play promoting real relationship signaling spss target tissue tissues trend value western wnt
Tagcloud (Intersection) ?