TFB2M and POLRMT

Number of citations of the paper that reports this interaction (PMID 12068295)
109

Data Source:
HPRD (in vitro)

		TFB2M	POLRMT
Gene Name		transcription factor B2, mitochondrial	polymerase (RNA) mitochondrial (DNA directed)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix Mitochondrial Nucleoid	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	RRNA (adenine-N6,N6-)-dimethyltransferase Activity Transcription Cofactor Activity Poly(A) RNA Binding	DNA Binding DNA-directed RNA Polymerase Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression RRNA Methylation Positive Regulation Of Transcription, DNA-templated	Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression
Pathways		Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis	Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: PNP POLRMT TFAM	2 interactors: TFB1M TFB2M
Entrez ID		64216	5442
HPRD ID		09520	03468
Ensembl ID		ENSG00000162851	ENSG00000099821
Uniprot IDs		Q9H5Q4	O00411 Q4G0F4
PDB IDs			3SPA 4BOC
Enriched GO Terms of Interacting Partners?		Transcription Initiation From Mitochondrial Promoter Transcription From Mitochondrial Promoter NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Inosine Catabolic Process Nicotinamide Riboside Catabolic Process Interleukin-2 Secretion Urate Biosynthetic Process DNA-templated Transcription, Initiation Mitochondrion Organization Interleukin-2 Production Urate Metabolic Process Purine Ribonucleoside Catabolic Process Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Appetite Purine-containing Compound Salvage Mitochondrial Respiratory Chain Complex Assembly NAD Biosynthetic Process Cytokine Secretion Purine Nucleotide Catabolic Process Purine Nucleobase Metabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation NAD Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nucleotide Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Differentiation Nicotinamide Nucleotide Metabolic Process Neuropeptide Signaling Pathway Positive Regulation Of Lymphocyte Differentiation Feeding Behavior Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Digestion Protein Secretion Regulation Of T Cell Differentiation Cytokine Production Regulation Of T Cell Proliferation Organophosphate Catabolic Process Coenzyme Biosynthetic Process	RRNA Methylation RRNA Modification RNA Methylation RRNA Processing RRNA Metabolic Process RNA Modification Ribosome Biogenesis Ribonucleoprotein Complex Biogenesis Transcription Initiation From Mitochondrial Promoter Mitochondrion Organization Methylation NcRNA Metabolic Process Transcription From Mitochondrial Promoter Transcription, DNA-templated RNA Biosynthetic Process
Tagcloud ?			c17orf42 coincident comprising dead dhx30 dsdna elongation foci helicase hereafter hhh incompetence makes mitochondria mitochondrial motifs owing pentatricopeptide processivity ptcd3 purification ribonuclease rnase spt6 ss strand tefm templates transcripts
Tagcloud (Difference) ?			c17orf42 coincident comprising dead dhx30 dsdna elongation foci helicase hereafter hhh incompetence makes mitochondria mitochondrial motifs owing pentatricopeptide processivity ptcd3 purification ribonuclease rnase spt6 ss strand tefm templates transcripts
Tagcloud (Intersection) ?