TFB2M and TFAM

Number of citations of the paper that reports this interaction (PMID 12068295)
109

Data Source:
HPRD (in vitro)

		TFB2M	TFAM
Gene Name		transcription factor B2, mitochondrial	transcription factor A, mitochondrial
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix Mitochondrial Nucleoid	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid
	Molecular Function	RRNA (adenine-N6,N6-)-dimethyltransferase Activity Transcription Cofactor Activity Poly(A) RNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding DNA Binding, Bending Heat Shock Protein Binding Poly(A) RNA Binding Mitochondrial Light Strand Promoter Sense Binding
	Biological Process	Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression RRNA Methylation Positive Regulation Of Transcription, DNA-templated	DNA-dependent DNA Replication Chromatin Remodeling Regulation Of Transcription From RNA Polymerase I Promoter Transcription From Mitochondrial Promoter Transcription Initiation From Mitochondrial Promoter Organelle Organization Mitochondrion Organization Gene Expression Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis	Organelle biogenesis and maintenance Mitochondrial transcription initiation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Transcription from mitochondrial promoters Transcriptional activation of mitochondrial biogenesis Mitochondrial biogenesis
Drugs
Diseases
GWAS			Height ( 23456168)
Protein-Protein Interactions		3 interactors: PNP POLRMT TFAM	5 interactors: AGTRAP ARL6IP1 PNP TFB1M TFB2M
Entrez ID		64216	7019
HPRD ID		09520	02702
Ensembl ID		ENSG00000162851	ENSG00000108064
Uniprot IDs		Q9H5Q4	E5KSU5 Q00059
PDB IDs			3FGH 3TMM 3TQ6
Enriched GO Terms of Interacting Partners?		Transcription Initiation From Mitochondrial Promoter Transcription From Mitochondrial Promoter NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Inosine Catabolic Process Nicotinamide Riboside Catabolic Process Interleukin-2 Secretion Urate Biosynthetic Process DNA-templated Transcription, Initiation Mitochondrion Organization Interleukin-2 Production Urate Metabolic Process Purine Ribonucleoside Catabolic Process Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Appetite Purine-containing Compound Salvage Mitochondrial Respiratory Chain Complex Assembly NAD Biosynthetic Process Cytokine Secretion Purine Nucleotide Catabolic Process Purine Nucleobase Metabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation NAD Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Nucleotide Catabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of T Cell Proliferation Positive Regulation Of T Cell Differentiation Nicotinamide Nucleotide Metabolic Process Neuropeptide Signaling Pathway Positive Regulation Of Lymphocyte Differentiation Feeding Behavior Nitrogen Compound Metabolic Process DNA-dependent DNA Replication Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Digestion Protein Secretion Regulation Of T Cell Differentiation Cytokine Production Regulation Of T Cell Proliferation Organophosphate Catabolic Process Coenzyme Biosynthetic Process	RRNA Methylation RRNA Modification RNA Methylation NAD Biosynthesis Via Nicotinamide Riboside Salvage Pathway Inosine Catabolic Process Nicotinamide Riboside Catabolic Process RRNA Processing RRNA Metabolic Process Interleukin-2 Secretion Urate Biosynthetic Process RNA Modification Transcription Initiation From Mitochondrial Promoter Ribosome Biogenesis Angiotensin-activated Signaling Pathway Ribonucleoprotein Complex Biogenesis Interleukin-2 Production Transcription From Mitochondrial Promoter Urate Metabolic Process Purine Ribonucleoside Catabolic Process Mitochondrion Organization Methylation NcRNA Metabolic Process Regulation Of Appetite Purine-containing Compound Salvage NAD Biosynthetic Process Cytokine Secretion Purine Nucleotide Catabolic Process Purine Nucleobase Metabolic Process Positive Regulation Of Alpha-beta T Cell Differentiation NAD Metabolic Process
Tagcloud ?			analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin
Tagcloud (Difference) ?			analogs apoptogenic biogenesis coded counterpart diminished dissipation doses her2high inducer innovation lowered mitocans mitochondrial mitochondrially mitoves mtdna replicated respiration succinate suppress suppresses targeted tocopheryl transcript transcripts unlike untargeted vitamin
Tagcloud (Intersection) ?