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CNTROB and LYST
Number of citations of the paper that reports this interaction (PubMedID
11984006
)
0
Data Source:
HPRD
(two hybrid)
CNTROB
LYST
Description
centrobin, centriole duplication and spindle assembly protein
lysosomal trafficking regulator
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Centriole
Cytosol
Cytoskeleton
Ciliary Basal Body
Cytoplasm
Microtubule Cytoskeleton
Molecular Function
Protein Binding
Protein Domain Specific Binding
Protein Binding
Biological Process
Centriole Replication
Centrosome Separation
Cell Division
Regulation Of Cilium Assembly
Mitotic Cytokinetic Process
Lymphocyte Mediated Immunity
Phagocytosis
Immune Response
Protein Transport
Leukocyte Chemotaxis
Melanosome Organization
Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway
Mast Cell Secretory Granule Organization
Natural Killer Cell Mediated Cytotoxicity
Defense Response To Bacterium
Defense Response To Protozoan
Pigmentation
Defense Response To Virus
Defense Response To Other Organism
Pathways
Drugs
Diseases
Other phagocyte defects, including the following eight diseases: Chediak-Higashi syndrome; Griscelli syndrome, type 1 (GS1); Griscelli syndrome, type 2 (GS2); Griscelli syndrome, type 3 (GS3); beta-actin deficiency; Neutrophil-specific granule deficiency; Myeloperoxidase deficiency; Glucose 6-phosphate dehydrogenase deficiency; Shwachman syndrome
GWAS
Refractive error (
32231278
)
Basophil percentage of white cells (
32888494
)
Lymphocyte count (
32888494
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Systemic lupus erythematosus (
19838195
26502338
)
Interacting Genes
20 interacting genes:
APTX
COASY
CWF19L2
DAPK1
DUSP29
ELOA
EPM2AIP1
GSK3A
LYST
MCRS1
PELI1
PNKP
RAD23A
RSPH14
SMARCA2
SYT6
TCEA2
TSC1
TSHZ2
TTC23
23 interacting genes:
ATN1
CALM1
CELF4
CNTROB
CPAP
CSNK2B
DNAJC14
EFS
ESRRA
ESS2
HGS
HNRNPM
KPNB1
MED12
MRPL17
MRPS31
NCDN
PCBP4
TNNI3
VTA1
YWHAB
YWHAQ
ZNF521
Entrez ID
116840
1130
HPRD ID
13991
06060
Ensembl ID
ENSG00000170037
ENSG00000143669
Uniprot IDs
Q8N137
Q99698
PDB IDs
Enriched GO Terms of Interacting Partners
?
Polynucleotide 3'-phosphatase Activity
DNA Metabolic Process
DNA Repair
Positive Regulation Of DNA Repair
Damaged DNA Binding
Nucleic Acid Metabolic Process
Nucleobase-containing Compound Metabolic Process
Negative Regulation Of TOR Signaling
Regulation Of DNA Repair
Positive Regulation Of Double-strand Break Repair
DNA Damage Response
Positive Regulation Of DNA Metabolic Process
Cellular Response To Stress
DAPK1-calmodulin Complex
Macromolecule Metabolic Process
Positive Regulation Of Autophagic Cell Death
Negative Regulation Of UDP-glucose Catabolic Process
Regulation Of Glycogen Metabolic Process
Regulation Of TOR Signaling
Regulation Of Glycogen Biosynthetic Process
Response To Insulin
Regulation Of Double-strand Break Repair
Memory T Cell Differentiation
DNA-3'-diphospho-5'-guanosine Diphosphatase
Single-strand Break-containing DNA Binding
DNA 5'-adenosine Monophosphate Hydrolase Activity
Pantetheine-phosphate Adenylyltransferase Activity
Protein Domain Specific Binding
Regulation Of Receptor Signaling Pathway Via JAK-STAT
Calcium Channel Inhibitor Activity
Astral Microtubule Organization
Ribonucleoprotein Complex
Alternative MRNA Splicing, Via Spliceosome
Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Centriole Replication
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Splicing
Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling
Multivesicular Body Organization
Multivesicular Body Assembly
Centriole Assembly
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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