CNTROB and COASY

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		CNTROB	COASY
Description		centrobin, centriole duplication and spindle assembly protein	Coenzyme A synthase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Ciliary Basal Body	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Extracellular Exosome
	Molecular Function	Protein Binding Protein Domain Specific Binding	Nucleotide Binding Catalytic Activity Dephospho-CoA Kinase Activity Pantetheine-phosphate Adenylyltransferase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Nucleotidyltransferase Activity
	Biological Process	Centriole Replication Centrosome Separation Cell Division Regulation Of Cilium Assembly Mitotic Cytokinetic Process	Coenzyme A Biosynthetic Process
Pathways			Coenzyme A biosynthesis
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Medication use (drugs used in diabetes) ( 31015401) Metabolic syndrome ( 31589552)
Interacting Genes		20 interacting genes: APTX COASY CWF19L2 DAPK1 DUSP29 ELOA EPM2AIP1 GSK3A LYST MCRS1 PELI1 PNKP RAD23A RSPH14 SMARCA2 SYT6 TCEA2 TSC1 TSHZ2 TTC23	12 interacting genes: APP BTK CFTR CNTROB KIAA1958 KRT20 LYN PJA1 RPS6KB1 RPS6KB2 SRC SYK
Entrez ID		116840	80347
HPRD ID		13991	13080
Ensembl ID		ENSG00000170037	ENSG00000068120
Uniprot IDs		Q8N137	Q13057
PDB IDs
Enriched GO Terms of Interacting Partners?		Polynucleotide 3'-phosphatase Activity DNA Metabolic Process DNA Repair Positive Regulation Of DNA Repair Damaged DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of TOR Signaling Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair DNA Damage Response Positive Regulation Of DNA Metabolic Process Cellular Response To Stress DAPK1-calmodulin Complex Macromolecule Metabolic Process Positive Regulation Of Autophagic Cell Death Negative Regulation Of UDP-glucose Catabolic Process Regulation Of Glycogen Metabolic Process Regulation Of TOR Signaling Regulation Of Glycogen Biosynthetic Process Response To Insulin Regulation Of Double-strand Break Repair Memory T Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Pantetheine-phosphate Adenylyltransferase Activity	Signaling Receptor Activator Activity Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Fc Receptor Signaling Pathway TORC1 Signaling Phospholipase Binding Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin TOR Signaling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-epsilon Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Ephrin Receptor Binding Protein Kinase Activity Negative Regulation Of Inflammatory Response To Antigenic Stimulus Cellular Response To Oxygen-containing Compound Regulation Of Vesicle-mediated Transport Fc-gamma Receptor Signaling Pathway Protein Tyrosine Kinase Activity Cellular Response To Molecule Of Fungal Origin Integrin Binding Kinase Activity Histamine Secretion By Mast Cell Protein Phosphorylation Response To Molecule Of Fungal Origin Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Pattern Recognition Receptor Signaling Pathway Cellular Developmental Process Phosphorylation B Cell Receptor Signaling Pathway Positive Regulation Of Cell Activation Innate Immune Response-activating Signaling Pathway Histamine Secretion Regulation Of Inflammatory Response Regulation Of Innate Immune Response Glial Cell Development Activation Of Innate Immune Response Positive Regulation Of TORC1 Signaling Negative Regulation Of TORC1 Signaling Membrane Raft Response To Lipid Positive Regulation Of Defense Response Histamine Transport Cellular Response To Lipid Positive Regulation Of Protein Metabolic Process Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Scaffold Protein Binding Positive Regulation Of Developmental Process Phospholipase Activator Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?