CNTROB and RSPH14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CNTROB	RSPH14
Description		centrobin, centriole duplication and spindle assembly protein	radial spoke head 14 homolog
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Ciliary Basal Body	Radial Spoke Cytoplasm Cytoskeleton Cilium Motile Cilium Cell Projection
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding
	Biological Process	Centriole Replication Centrosome Separation Cell Division Regulation Of Cilium Assembly Mitotic Cytokinetic Process
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Serum parathyroid hormone levels ( 27927781)
Interacting Genes		20 interacting genes: APTX COASY CWF19L2 DAPK1 DUSP29 ELOA EPM2AIP1 GSK3A LYST MCRS1 PELI1 PNKP RAD23A RSPH14 SMARCA2 SYT6 TCEA2 TSC1 TSHZ2 TTC23	40 interacting genes: ABI2 AGAP1 ALS2CL AP1M1 AP2M1 BPIFA1 CCDC102B CDR2 CNTROB COG6 EPS8 FHL3 GABPB1 GOLGA2 JUP KASH5 KIFC3 KRT15 KRT31 KRT40 KRT75 KRT76 LZTS1 MNS1 PIBF1 POLR1C REL RPH3AL RSPH3 SEPTIN12 SMAD4 TCF4 TRAF2 TRIM27 TRIM50 TRIM69 TRIM7 VPS9D1 ZNF474 ZNF629
Entrez ID		116840	27156
HPRD ID		13991	16136
Ensembl ID		ENSG00000170037	ENSG00000100218
Uniprot IDs		Q8N137	Q9UHP6
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Polynucleotide 3'-phosphatase Activity DNA Metabolic Process DNA Repair Positive Regulation Of DNA Repair Damaged DNA Binding Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of TOR Signaling Regulation Of DNA Repair Positive Regulation Of Double-strand Break Repair DNA Damage Response Positive Regulation Of DNA Metabolic Process Cellular Response To Stress DAPK1-calmodulin Complex Macromolecule Metabolic Process Positive Regulation Of Autophagic Cell Death Negative Regulation Of UDP-glucose Catabolic Process Regulation Of Glycogen Metabolic Process Regulation Of TOR Signaling Regulation Of Glycogen Biosynthetic Process Response To Insulin Regulation Of Double-strand Break Repair Memory T Cell Differentiation DNA-3'-diphospho-5'-guanosine Diphosphatase Single-strand Break-containing DNA Binding DNA 5'-adenosine Monophosphate Hydrolase Activity Pantetheine-phosphate Adenylyltransferase Activity	Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Cytoskeleton Organization Supramolecular Fiber Organization Cytoskeleton Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Organelle Organization Structural Molecule Activity Protein Binding Identical Protein Binding Zonula Adherens Sebaceous Gland Development Clathrin Adaptor Complex Centrosome Separation Positive Regulation Of Actin Nucleation Small GTPase Binding Innate Immune Response Epithelial Cell-cell Adhesion Clathrin Adaptor Activity
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