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GTF2F1 and CCNT1
Number of citations of the paper that reports this interaction (PubMedID
12591939
)
39
Data Source:
BioGRID
(enzymatic study)
GTF2F1
CCNT1
Description
general transcription factor IIF subunit 1
cyclin T1
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor TFIID Complex
Transcription Factor TFIIF Complex
Cell Junction
Protein-containing Complex
Nucleus
Nucleoplasm
Nucleolus
Cytosol
Cyclin/CDK Positive Transcription Elongation Factor Complex
P-TEFb Complex
Molecular Function
RNA Polymerase II General Transcription Initiation Factor Binding
TFIIF-class Transcription Factor Complex Binding
DNA Binding
RNA Binding
Protein Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Phosphatase Activator Activity
Protein Phosphatase Binding
Protein Domain Specific Binding
Promoter-specific Chromatin Binding
Transcription Cis-regulatory Region Binding
DNA Binding
Chromatin Binding
Protein Binding
Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
SnRNA Binding
Protein Kinase Binding
Cyclin-dependent Protein Serine/threonine Kinase Activator Activity
RNA Polymerase Binding
7SK SnRNA Binding
DNA-binding Transcription Factor Binding
Molecular Condensate Scaffold Activity
Biological Process
Transcription By RNA Polymerase II
Transcription Initiation At RNA Polymerase II Promoter
Transcription Elongation By RNA Polymerase II
Response To Virus
Negative Regulation Of Protein Binding
Positive Regulation Of Transcription Elongation By RNA Polymerase II
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Response To Xenobiotic Stimulus
Positive Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Transcription Elongation By RNA Polymerase II
Host-mediated Activation Of Viral Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Cell Division
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Interactions of Tat with host cellular proteins
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Clozapine-induced agranulocytosis (
25187353
)
Interacting Genes
34 interacting genes:
ABL1
AHR
AR
ARNT
ATF7IP
BCL2L13
CCNT1
CDK9
CEBPA
CFTR
CSNK2A1
CTDP1
CTDSP1
DAPK1
FEZ1
FNDC3B
FOS
GTF2A1
GTF2B
GTF2E1
GTF2E2
GTF2F2
GTF2H4
JUN
MAGEC1
MSX2
MYC
PARP1
PSMC2
PTN
SRF
TAF1
TAF11
TRIM27
24 interacting genes:
AFF4
AHR
BRD4
CDK9
ESR1
GRIPAP1
GRN
GTF2F1
HEXIM1
HEXIM2
HIC2
HTATSF1
HTN1
KAT2B
MDFIC
MYC
NCOA2
NUFIP1
PML
POLR2A
PRKCI
PURA
RN7SK
SKP2
Entrez ID
2962
904
HPRD ID
01803
03938
Ensembl ID
ENSG00000125651
ENSG00000129315
Uniprot IDs
P35269
A8K4M5
O60563
PDB IDs
1F3U
1I27
1J2X
1NHA
1ONV
2K7L
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6O9L
7EDX
7EG7
7EG8
7EG9
7EGA
7EGB
7EGC
7ENA
7ENC
7LBM
7NVR
7NVS
7NVT
7NVU
7NVY
7NVZ
7NW0
7ZWD
7ZX7
7ZX8
8BVW
8BYQ
8BZ1
8GXQ
8GXS
8S51
8S52
8S54
8S55
8S5N
8WAK
8WAL
8WAN
8WAO
8WAP
8WAQ
8WAR
8WAS
8WAT
8WAU
8WAV
8WAW
8WAX
8WAY
8WAZ
8WB0
2PK2
3BLH
3BLQ
3BLR
3LQ5
3MI9
3MIA
3MY1
3TN8
3TNH
3TNI
4BCF
4BCG
4BCH
4BCI
4BCJ
4EC8
4EC9
4IMY
4OGR
4OR5
5L1Z
6CYT
6GZH
6W9E
6Z45
7NWK
8I0L
8K5R
Enriched GO Terms of Interacting Partners
?
Transcription By RNA Polymerase II
DNA-templated Transcription
RNA Polymerase II General Transcription Initiation Factor Activity
Transcription Initiation At RNA Polymerase II Promoter
Nucleobase-containing Compound Biosynthetic Process
Transcription Factor TFIID Complex
DNA-templated Transcription Initiation
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Regulation Of Transcription By RNA Polymerase II
RNA Metabolic Process
Nucleus
Positive Regulation Of DNA-templated Transcription Initiation
Nucleoplasm
Host-mediated Activation Of Viral Transcription
Regulation Of DNA-templated Transcription Initiation
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Macromolecule Biosynthetic Process
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription Regulator Complex
Nucleic Acid Metabolic Process
TBP-class Protein Binding
Positive Regulation Of RNA Metabolic Process
DNA Binding
Host-mediated Perturbation Of Viral Transcription
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Host-mediated Activation Of Viral Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Transcription Cis-regulatory Region Binding
Positive Regulation Of MiRNA Transcription
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Primary Metabolic Process
Positive Regulation Of MiRNA Metabolic Process
Positive Regulation Of Transcription Initiation By RNA Polymerase II
Positive Regulation Of Metabolic Process
RNA Polymerase II General Transcription Initiation Factor Binding
RNA Polymerase II Transcription Regulator Complex
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Transcription Initiation By RNA Polymerase II
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of MiRNA Transcription
Host-mediated Perturbation Of Viral Process
Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of DNA-templated Transcription
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of DNA-templated Transcription
Negative Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Nucleoplasm
Regulation Of RNA Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Macromolecule Metabolic Process
Regulation Of Primary Metabolic Process
Regulation Of Gene Expression
7SK SnRNA Binding
Regulation Of Transcription Elongation By RNA Polymerase II
Regulation Of Macromolecule Biosynthetic Process
Regulation Of DNA-templated Transcription Elongation
SnRNA Binding
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Negative Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Transcription By RNA Polymerase II
Negative Regulation Of Metabolic Process
Transcription Elongation Factor Complex
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription Elongation By RNA Polymerase II
Nucleus
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Regulation Of Cellular Response To Stress
Negative Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
P-TEFb Complex Binding
7SK SnRNP
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Signal Transduction By P53 Class Mediator
DNA-templated Transcription
Rhythmic Process
Transcription Regulator Inhibitor Activity
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Transcription By RNA Polymerase II
Transcription Elongation By RNA Polymerase II
Transcription Coactivator Binding
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-templated Transcription Elongation
Protein-containing Complex
Positive Regulation Of Fibroblast Proliferation
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