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GTF2F1 and CCNT1
Number of citations of the paper that reports this interaction (PMID
12591939
)
5
Data Source:
BioGRID
(enzymatic study)
GTF2F1
CCNT1
Gene Name
general transcription factor IIF, polypeptide 1, 74kDa
cyclin T1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor TFIIF Complex
Cell Junction
Nucleus
Nucleoplasm
Nucleolus
Positive Transcription Elongation Factor Complex B
Molecular Function
DNA Binding
Transcription Coactivator Activity
Catalytic Activity
Protein Binding
Transcription Factor Binding
Phosphatase Activator Activity
Poly(A) RNA Binding
DNA Binding
Chromatin Binding
Protein Binding
SnRNA Binding
Protein Kinase Binding
Transcription Regulatory Region DNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
RNA Splicing
Response To Virus
Gene Expression
Viral Process
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Catalytic Activity
Positive Regulation Of Viral Transcription
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Protein Phosphorylation
Cell Cycle
Transforming Growth Factor Beta Receptor Signaling Pathway
Gene Expression
Viral Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Cell Division
Pathways
RNA Polymerase II Promoter Escape
mRNA Splicing
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Influenza Life Cycle
HIV elongation arrest and recovery
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Influenza Viral RNA Transcription and Replication
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Viral Messenger RNA Synthesis
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Loss of Function of TGFBR2 in Cancer
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
HIV Infection
SMAD2/3 MH2 Domain Mutants in Cancer
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
TGFBR1 LBD Mutants in Cancer
RNA Polymerase II Pre-transcription Events
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
HIV elongation arrest and recovery
HIV Life Cycle
Generic Transcription Pathway
HIV Transcription Elongation
TGFBR2 MSI Frameshift Mutants in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
Host Interactions of HIV factors
Loss of Function of SMAD4 in Cancer
Interactions of Tat with host cellular proteins
TGFBR1 KD Mutants in Cancer
Pausing and recovery of Tat-mediated HIV elongation
Loss of Function of TGFBR1 in Cancer
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Transcription of the HIV genome
SMAD4 MH2 Domain Mutants in Cancer
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions
31 interactors:
ABL1
AHR
AR
ARNT
ATF7IP
CCNT1
CDK9
CSNK2A1
CTDP1
CTDSP1
FCP1
FEZ1
FOS
GTF2A1
GTF2B
GTF2E2
GTF2F2
GTF2H4
JUN
KLF5
MAGEC1
MSX2
MYC
PARP1
PSMC2
PTN
SRF
TAF1
TAF11
TBP
TRIM27
26 interactors:
AFF4
AHR
BRD4
CDK9
CTD
ESR1
GRIPAP1
GRN
GTF2F1
HEXIM1
HEXIM2
HIC2
HTATSF1
HTN1
KAT2B
MBP
MDFIC
MYC
NCOA2
NUFIP1
PML
POLR2A
PURA
RN7SK
SKP2
SUPT5H
Entrez ID
2962
904
HPRD ID
01803
03938
Ensembl ID
ENSG00000125651
ENSG00000129315
Uniprot IDs
P35269
A8K4M5
A9XU13
O60563
PDB IDs
1F3U
1I27
1J2X
1NHA
1ONV
2K7L
2PK2
3BLH
3BLQ
3BLR
3LQ5
3MI9
3MIA
3MY1
3TN8
3TNH
3TNI
4BCF
4BCG
4BCH
4BCI
4BCJ
4EC8
4EC9
4IMY
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Transcription, DNA-templated
DNA-templated Transcription, Elongation
RNA Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
DNA-templated Transcription, Initiation
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Viral Transcription
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Gene Expression
Positive Regulation Of Viral Transcription
Regulation Of Nucleic Acid-templated Transcription
Viral Process
Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Viral Process
Regulation Of Viral Process
Positive Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Cellular Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Regulation Of DNA-templated Transcription, Initiation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Regulation Of Cellular Component Organization
Negative Regulation Of Biosynthetic Process
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Regulation Of Cell Proliferation
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Cellular Macromolecule Biosynthetic Process
Regulation Of Transcription, DNA-templated
Macromolecule Biosynthetic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Positive Regulation Of Viral Transcription
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Viral Process
Cellular Nitrogen Compound Metabolic Process
Transcription From RNA Polymerase II Promoter
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Viral Transcription
Regulation Of Viral Process
Positive Regulation Of Viral Process
Positive Regulation Of Cellular Biosynthetic Process
Nitrogen Compound Metabolic Process
Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
DNA-templated Transcription, Initiation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Regulation Of DNA-templated Transcription, Elongation
Negative Regulation Of Cell Cycle
Transcription Elongation From RNA Polymerase II Promoter
Chromatin Remodeling
DNA-templated Transcription, Elongation
Regulation Of Metabolic Process
Regulation Of Cell Cycle
Positive Regulation Of DNA-templated Transcription, Elongation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
7-methylguanosine MRNA Capping
Positive Regulation Of Metabolic Process
Tagcloud
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
shank1
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Difference)
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
shank1
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Intersection)
?