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GTF2F1 and GTF2H4
Number of citations of the paper that reports this interaction (PMID
9159119
)
77
Data Source:
BioGRID
(biochemical, pull down)
GTF2F1
GTF2H4
Gene Name
general transcription factor IIF, polypeptide 1, 74kDa
general transcription factor IIH, polypeptide 4, 52kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor TFIIF Complex
Cell Junction
Core TFIIH Complex
Nucleoplasm
Holo TFIIH Complex
Molecular Function
DNA Binding
Transcription Coactivator Activity
Catalytic Activity
Protein Binding
Transcription Factor Binding
Phosphatase Activator Activity
Poly(A) RNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
ATP-dependent DNA Helicase Activity
Protein Kinase Activity
Protein Binding
DNA-dependent ATPase Activity
RNA Polymerase II Carboxy-terminal Domain Kinase Activity
Biological Process
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
RNA Splicing
Response To Virus
Gene Expression
Viral Process
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Catalytic Activity
Positive Regulation Of Viral Transcription
Nucleotide-excision Repair, DNA Damage Removal
DNA Repair
Transcription-coupled Nucleotide-excision Repair
Nucleotide-excision Repair
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription Elongation From RNA Polymerase I Promoter
Termination Of RNA Polymerase I Transcription
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Protein Phosphorylation
Gene Expression
Viral Process
DNA Duplex Unwinding
Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Viral Transcription
Pathways
RNA Polymerase II Promoter Escape
mRNA Splicing
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription
Abortive elongation of HIV-1 transcript in the absence of Tat
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Influenza Life Cycle
HIV elongation arrest and recovery
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
Influenza Viral RNA Transcription and Replication
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Processing of Capped Intron-Containing Pre-mRNA
mRNA Capping
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Influenza Infection
Pausing and recovery of Tat-mediated HIV elongation
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
RNA Polymerase II Transcription Initiation And Promoter Clearance
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Viral Messenger RNA Synthesis
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
RNA Polymerase II Promoter Escape
Formation of HIV-1 elongation complex containing HIV-1 Tat
Nucleotide Excision Repair
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Clearance
HIV Infection
Formation of the Early Elongation Complex
Tat-mediated elongation of the HIV-1 transcript
Formation of transcription-coupled NER (TC-NER) repair complex
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II Pre-transcription Events
Dual incision reaction in TC-NER
NoRC negatively regulates rRNA expression
HIV Transcription Initiation
HIV Life Cycle
RNA Pol II CTD phosphorylation and interaction with CE
RNA Polymerase II HIV Promoter Escape
HIV Transcription Elongation
Dual incision reaction in GG-NER
mRNA Capping
RNA Polymerase I Transcription
RNA Polymerase I Promoter Escape
RNA Polymerase I Transcription Termination
Epigenetic regulation of gene expression
Negative epigenetic regulation of rRNA expression
Late Phase of HIV Life Cycle
Formation of RNA Pol II elongation complex
Global Genomic NER (GG-NER)
RNA Polymerase II Transcription Initiation And Promoter Clearance
Transcription-coupled NER (TC-NER)
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of incision complex in GG-NER
RNA Polymerase II Transcription Initiation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Ulcerative colitis (
20848476
)
Protein-Protein Interactions
31 interactors:
ABL1
AHR
AR
ARNT
ATF7IP
CCNT1
CDK9
CSNK2A1
CTDP1
CTDSP1
FCP1
FEZ1
FOS
GTF2A1
GTF2B
GTF2E2
GTF2F2
GTF2H4
JUN
KLF5
MAGEC1
MSX2
MYC
PARP1
PSMC2
PTN
SRF
TAF1
TAF11
TBP
TRIM27
10 interactors:
ERCC3
ERCC5
GTF2B
GTF2E1
GTF2F1
GTF2H3
POLR2A
TBP
TP53
XBP1P1
Entrez ID
2962
2968
HPRD ID
01803
03456
Ensembl ID
ENSG00000125651
ENSG00000213780
Uniprot IDs
P35269
Q92759
PDB IDs
1F3U
1I27
1J2X
1NHA
1ONV
2K7L
Enriched GO Terms of Interacting Partners
?
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Transcription, DNA-templated
DNA-templated Transcription, Elongation
RNA Biosynthetic Process
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
DNA-templated Transcription, Initiation
RNA Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Cellular Nitrogen Compound Metabolic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Viral Transcription
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Nitrogen Compound Metabolic Process
Regulation Of Transcription, DNA-templated
Positive Regulation Of Gene Expression
Positive Regulation Of Viral Transcription
Regulation Of Nucleic Acid-templated Transcription
Viral Process
Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Viral Process
Regulation Of Viral Process
Positive Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Transcription, DNA-templated
Cellular Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Cellular Metabolic Process
Regulation Of DNA-templated Transcription, Initiation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
Regulation Of Cellular Component Organization
Negative Regulation Of Biosynthetic Process
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Regulation Of Cell Proliferation
Transcription Elongation From RNA Polymerase II Promoter
DNA-templated Transcription, Elongation
Transcription Initiation From RNA Polymerase II Promoter
DNA-templated Transcription, Initiation
Viral Process
Transcription From RNA Polymerase II Promoter
Nucleotide-excision Repair
7-methylguanosine MRNA Capping
7-methylguanosine RNA Capping
Transcription-coupled Nucleotide-excision Repair
Positive Regulation Of Viral Transcription
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Nucleotide-excision Repair, DNA Damage Removal
Transcription, DNA-templated
RNA Biosynthetic Process
Termination Of RNA Polymerase I Transcription
Transcription Elongation From RNA Polymerase I Promoter
Transcription Initiation From RNA Polymerase I Promoter
Transcription From RNA Polymerase I Promoter
Regulation Of Viral Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
RNA Metabolic Process
DNA Repair
Gene Expression
Nitrogen Compound Metabolic Process
Nucleotide-excision Repair, DNA Incision
Cellular Macromolecule Biosynthetic Process
DNA-templated Transcription, Termination
Negative Regulation Of Gene Expression, Epigenetic
Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
MRNA Processing
UV Protection
Response To UV
DNA Catabolic Process
DNA Metabolic Process
Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Tagcloud
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
shank1
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Difference)
?
akap6
atf7
atxn1
bmpr2
categorize
deltan
eef1a1
grip2
interactors
jbd
jbds
jnk1alpha1
jnk3
jnk3alpha1
jnks
kcne4
myo9b
nnat
pias1
ptgds
ptpn2
rabgap1
rusc2
shank1
sumo1
sypl1
tkt
topbp1
znf668
Tagcloud (Intersection)
?