TAF4B and TAF1

Number of citations of the paper that reports this interaction (PMID 15601843)
24

Data Source:
BioGRID (pull down)

		TAF4B	TAF1
Gene Name		TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Nucleolus Cytoplasm	Nucleoplasm Transcription Factor TFIID Complex MLL1 Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Heterodimerization Activity NF-kappaB Binding	P53 Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Transcription Factor Binding TBP-class Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Lysine-acetylated Histone Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Spermatogenesis Gene Expression Viral Process Oogenesis	DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Cell Cycle Gene Expression Viral Process Histone Acetylation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autophosphorylation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552) Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		5 interactors: GTF2A1 HIST3H3 RELA TAF1 TAF12	47 interactors: APC AR ASF1A ASF1B BRMS1 CCNA2 CCND1 EDF1 EWSR1 FOS GFI1B GTF2A1 GTF2E1 GTF2F1 HIST1H3A HIST1H4A HIST3H3 HMGB1 HSF1 JUN MAX MDM2 MSX1 PAX3 RANBP2 RB1 RBL1 RBL2 RELA SUB1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF7L TAF8 TAF9 TBP TP53 UBE2I UBTF
Entrez ID		6875	6872
HPRD ID		19270	02436
Ensembl ID		ENSG00000141384	ENSG00000147133
Uniprot IDs		J3KTH2 Q92750	P21675
PDB IDs			1EQF 3AAD 3UV4 3UV5
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Viral Process Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Acetaldehyde Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Nucleobase-containing Compound Metabolic Process Protein Acetylation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Schwann Cell Differentiation Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Schwann Cell Differentiation RNA Polymerase II Transcriptional Preinitiation Complex Assembly Nitrogen Compound Metabolic Process Chromosome Organization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Cobalamin Peptidyl-lysine Modification Positive Regulation Of MiRNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway RNA Metabolic Process Cellular Response To Nicotine Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Gene Expression Regulation Of MiRNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Protein Catabolic Process Macromolecule Biosynthetic Process Histone Modification Regulation Of Interleukin-12 Biosynthetic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Response To Muramyl Dipeptide Response To UV-B Membrane Protein Intracellular Domain Proteolysis Positive Regulation Of DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Regulation Of DNA-templated Transcription, Initiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway	RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Elongation Transcription Elongation From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Viral Process Regulation Of Metabolic Process Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Chromatin Organization Positive Regulation Of Cellular Metabolic Process Chromosome Organization Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Chromatin Modification Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organelle Organization Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity DNA Replication-dependent Nucleosome Assembly Mitotic Cell Cycle
Tagcloud ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf2 taf9 tafs tata tfiid	3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf7 tata tfiid trimethylated
Tagcloud (Difference) ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf2 taf9 tafs	3d acetyltransferase acetyltransferases architecture assembly cofolding displays dissociable ensures heterodimer integral lys27 machinery mark marks multiprotein neighboring nucleates obvious pic pockets preinitiation reading similarities taf7 trimethylated
Tagcloud (Intersection) ?		tata tfiid