TAF4B

Description		TATA-box binding protein associated factor 4b
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm
	Molecular Function	DNA Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity NF-kappaB Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	DNA-templated Transcription DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Spermatogenesis Cell Differentiation MRNA Transcription By RNA Polymerase II Oogenesis RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Asthma-chronic obstructive pulmonary disease overlap syndrome ( 30657218) Bell's palsy ( 33602968) Cirrhosis (alcohol related) ( 32853455) Femur bone mineral density x serum urate levels interaction ( 34046847) Red blood cell count ( 32888494) Rhegmatogenous retinal detachment ( 23585552) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		4 interacting genes: GTF2A1 H3-4 RELA TAF1
Entrez ID		6875
HPRD ID		19270
Ensembl ID		ENSG00000141384
Uniprot IDs		B4DYT3 J3KTH2 Q92750
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding Protein-DNA Complex Assembly TBP-class Protein Binding Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity RNA Polymerase II Preinitiation Complex Assembly Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Post-translational Protein Modification DNA Binding Positive Regulation Of Androgen Receptor Signaling Pathway Response To Purine-containing Compound NF-kappaB P50/p65 Complex Chromatin Organization Negative Regulation Of Protein Autoubiquitination Nucleobase-containing Compound Biosynthetic Process Response To UV Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin RNA Polymerase II-specific DNA-binding Transcription Factor Binding Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Acetyl-CoA Binding Spermatogonial Cell Division Transcription Factor TFIIA Complex Transcription Regulator Complex Postsynapse To Nucleus Signaling Pathway Regulation Of Post-translational Protein Modification RNA Polymerase I General Transcription Initiation Factor Activity Histone H4K16ac Reader Activity Regulation Of Protein Autoubiquitination Protein-containing Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II Ankyrin Repeat Binding Cellular Response To Peptidoglycan DNA Replication-dependent Chromatin Assembly Transcription By RNA Polymerase II Cellular Response To Nicotine Transcription Initiation At RNA Polymerase I Promoter Protein-containing Complex Organization
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