TAF4B and GTF2A1

Number of citations of the paper that reports this interaction (PubMedID 15601843)
39

Data Source:
BioGRID (pull down)

		TAF4B	GTF2A1
Description		TATA-box binding protein associated factor 4b	general transcription factor IIA subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Cytoplasm Cytosol Transcription Preinitiation Complex
	Molecular Function	DNA Binding RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity NF-kappaB Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	DNA-templated Transcription DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Spermatogenesis Cell Differentiation MRNA Transcription By RNA Polymerase II Oogenesis RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Asthma-chronic obstructive pulmonary disease overlap syndrome ( 30657218) Bell's palsy ( 33602968) Cirrhosis (alcohol related) ( 32853455) Femur bone mineral density x serum urate levels interaction ( 34046847) Red blood cell count ( 32888494) Rhegmatogenous retinal detachment ( 23585552) Visceral adipose tissue adjusted for BMI ( 22589738)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Neutrophil count ( 32888494) Night sleep phenotypes ( 27126917) Thyroid stimulating hormone levels ( 32769997) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: GTF2A1 H3-4 RELA TAF1	26 interacting genes: BCL3 BIRC7 CREB1 CSNK2A1 CSNK2A2 GTF2A2 GTF2E1 GTF2E2 GTF2F1 HMGB1 NCOA6 NFYA PRR20A PRR20B PRR20C PRR20D PRR20E PSMC6 SP4 TAF1 TAF4 TAF4B TASP1 TBP TBPL1 TRIP4
Entrez ID		6875	2957
HPRD ID		19270	02748
Ensembl ID		ENSG00000141384	ENSG00000165417
Uniprot IDs		B4DYT3 J3KTH2 Q92750	P52655
PDB IDs			1NVP 5FUR 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5M4S 6MZM 6O9L 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGI 7EGJ 7LBM 7NVR 7NVS 7NVT 7NVU 7NVY 7NVZ 7NW0 7ZWC 7ZWD 7ZX7 7ZX8 7ZXE 8BVW 8BYQ 8BZ1 8GXQ 8GXS 8S51 8S52 8S5N 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II General Transcription Initiation Factor Binding Protein-DNA Complex Assembly TBP-class Protein Binding Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity Protein Heterodimerization Activity RNA Polymerase II Preinitiation Complex Assembly Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Post-translational Protein Modification DNA Binding Positive Regulation Of Androgen Receptor Signaling Pathway Response To Purine-containing Compound NF-kappaB P50/p65 Complex Chromatin Organization Negative Regulation Of Protein Autoubiquitination Nucleobase-containing Compound Biosynthetic Process Response To UV Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin RNA Polymerase II-specific DNA-binding Transcription Factor Binding Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Acetyl-CoA Binding Spermatogonial Cell Division Transcription Factor TFIIA Complex Transcription Regulator Complex Postsynapse To Nucleus Signaling Pathway Regulation Of Post-translational Protein Modification RNA Polymerase I General Transcription Initiation Factor Activity Histone H4K16ac Reader Activity Regulation Of Protein Autoubiquitination Protein-containing Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II Ankyrin Repeat Binding Cellular Response To Peptidoglycan DNA Replication-dependent Chromatin Assembly Transcription By RNA Polymerase II Cellular Response To Nicotine Transcription Initiation At RNA Polymerase I Promoter Protein-containing Complex Organization	RNA Polymerase II General Transcription Initiation Factor Activity DNA-templated Transcription Initiation Transcription Factor TFIID Complex Transcription Initiation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation DNA-templated Transcription Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Nucleobase-containing Compound Biosynthetic Process RNA Polymerase II General Transcription Initiation Factor Binding RNA Metabolic Process Nucleic Acid Metabolic Process Macromolecule Biosynthetic Process MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly RNA Polymerase II-specific DNA-binding Transcription Factor Binding MRNA Transcription Transcription Factor TFIIA Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Metabolic Process Nucleoplasm Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Biosynthetic Process Transcription Factor TFIIE Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RNA Polymerase II Core Promoter Sequence-specific DNA Binding Regulation Of Transcription By RNA Polymerase II Protein Kinase CK2 Complex Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process Protein-DNA Complex Assembly Nucleus Positive Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Aryl Hydrocarbon Receptor Binding Male Germ Cell Nucleus Regulation Of Gene Expression
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