TAF2 and TAF5

Number of citations of the paper that reports this interaction (PMID 14580349)
15

Data Source:
HPRD (in vivo, in vitro)

		TAF2	TAF5
Gene Name		TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus Actin Cytoskeleton Transcription Factor TFTC Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Metallopeptidase Activity Zinc Ion Binding Transcription Regulatory Region DNA Binding	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Dimerization Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Proteolysis Gene Expression Response To Organic Cyclic Compound Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Chromatin Modification Histone Acetylation
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ESR1 HIST3H3 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9	18 interactors: CPSF1 GTF2F2 HIST3H3 MYC TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF6 TAF7 TAF8 TAF9 TAF9B TBP UBE2I
Entrez ID		6873	6877
HPRD ID		07060	11876
Ensembl ID		ENSG00000064313	ENSG00000148835
Uniprot IDs		B3KMD8 Q6P1X5	Q15542
PDB IDs			2NXP
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Nitrogen Compound Metabolic Process Protein Acetylation Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Chromosome Organization Regulation Of Transcription, DNA-templated Chromatin Modification Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Organization Histone Modification Histone H3 Acetylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Organelle Organization Spermine Transport Ovarian Follicle Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Steroid Hormone Receptor Signaling Pathway Metabolic Process	Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Viral Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Histone Acetylation Peptidyl-lysine Modification Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Histone H3 Acetylation Protein Acetylation Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Chromatin Modification Chromosome Organization Histone Modification Chromatin Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Peptidyl-amino Acid Modification Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Response To DNA Damage Stimulus Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Tagcloud ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf4 taf4b taf9 tafs tata tfiid	adjacent amide axillary bre cancerous dss faah ggh glutamyl hazards hydrolase invasive kaplan meier pcaf pir pirin positively predicts pronouncedly qrt rfs signatures taf5l tumoral undifferentiated unfavorable verify warranting
Tagcloud (Difference) ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf4 taf4b taf9 tafs tata tfiid	adjacent amide axillary bre cancerous dss faah ggh glutamyl hazards hydrolase invasive kaplan meier pcaf pir pirin positively predicts pronouncedly qrt rfs signatures taf5l tumoral undifferentiated unfavorable verify warranting
Tagcloud (Intersection) ?