TAF2 and TAF6

Number of citations of the paper that reports this interaction (PMID 14580349)
15

Data Source:
HPRD (in vivo, in vitro)

		TAF2	TAF6
Gene Name		TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Protein Binding Metallopeptidase Activity Zinc Ion Binding Transcription Regulatory Region DNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Proteolysis Gene Expression Response To Organic Cyclic Compound Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Cell Proliferation Gene Expression Viral Process Negative Regulation Of Cell Cycle Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ESR1 HIST3H3 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9	24 interactors: AHR APP CIITA GTF2E1 HIST3H3 HNF4A NCOR1 NFYA NFYB NFYC NR1D2 RELA SH3KBP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF7 TAF8 TAF9 TAF9B
Entrez ID		6873	6878
HPRD ID		07060	11807
Ensembl ID		ENSG00000064313	ENSG00000106290
Uniprot IDs		B3KMD8 Q6P1X5	P49848
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Nitrogen Compound Metabolic Process Protein Acetylation Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Chromosome Organization Regulation Of Transcription, DNA-templated Chromatin Modification Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Organization Histone Modification Histone H3 Acetylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Organelle Organization Spermine Transport Ovarian Follicle Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Steroid Hormone Receptor Signaling Pathway Metabolic Process	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Viral Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Cellular Metabolic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Cellular Process Peptidyl-lysine Modification Rhythmic Process Histone H3 Acetylation Chromatin Modification Metabolic Process Histone Modification Chromosome Organization Chromatin Organization Negative Regulation Of Transcription, DNA-templated
Tagcloud ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf4 taf4b taf9 tafs tata tfiid	acting alternative choice cis comparative decisions define depletion dictate drives elements employ gain inducible microarray minigene modulate mutational nothing pivotal pol splice splicing taf6alpha taf6delta tfiid transcriptome triggering undefined
Tagcloud (Difference) ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf4 taf4b taf9 tafs tata	acting alternative choice cis comparative decisions define depletion dictate drives elements employ gain inducible microarray minigene modulate mutational nothing pivotal pol splice splicing taf6alpha taf6delta transcriptome triggering undefined
Tagcloud (Intersection) ?		tfiid