TAF2 and TAF4

Number of citations of the paper that reports this interaction (PMID 14580349)
15

Data Source:
HPRD (in vivo, in vitro)

		TAF2	TAF4
Gene Name		TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex	Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Protein Binding Metallopeptidase Activity Zinc Ion Binding Transcription Regulatory Region DNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Proteolysis Gene Expression Response To Organic Cyclic Compound Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of Transcription, DNA-templated
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ESR1 HIST3H3 RNPS1 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9	22 interactors: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 HIST3H3 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12
Entrez ID		6873	6874
HPRD ID		07060	11797
Ensembl ID		ENSG00000064313	ENSG00000130699
Uniprot IDs		B3KMD8 Q6P1X5	O00268
PDB IDs			1H3O 2P6V
Enriched GO Terms of Interacting Partners?		Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Nitrogen Compound Metabolic Process Protein Acetylation Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Peptidyl-lysine Modification Chromosome Organization Regulation Of Transcription, DNA-templated Chromatin Modification Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Chromatin Organization Histone Modification Histone H3 Acetylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Peptidyl-amino Acid Modification Positive Regulation Of Cellular Metabolic Process Organelle Organization Spermine Transport Ovarian Follicle Development Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Intracellular Steroid Hormone Receptor Signaling Pathway Metabolic Process	Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Positive Regulation By Host Of Viral Transcription Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Rhythmic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process RNA Polymerase II Transcriptional Preinitiation Complex Assembly Peptidyl-lysine Modification Interaction With Symbiont Regulation Of Cellular Process Histone H3 Acetylation Positive Regulation Of Viral Transcription Chromatin Modification Circadian Rhythm Chromosome Organization
Tagcloud ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf4 taf4b taf9 tafs tata tfiid	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs tfiid
Tagcloud (Difference) ?		cascades chemoresistance cofactor compose d2 dedifferentiation deleted deregulation directs drive execute expand granulosa helps hgsc initiator outline ovarian ovary paralog pluripotent serous strikingly taf4b taf9 tata	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12
Tagcloud (Intersection) ?		taf4 tafs tfiid