TAF2 and TAF4

Number of citations of the paper that reports this interaction (PubMedID 14580349)
0

Data Source:
HPRD (in vivo, in vitro)

		TAF2	TAF4
Description		TATA-box binding protein associated factor 2	TATA-box binding protein associated factor 4
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex	Chromatin Male Germ Cell Nucleus Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytosol Protein-containing Complex Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Transcription Cis-regulatory Region Binding Chromatin Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity	Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Aryl Hydrocarbon Receptor Binding Protein Heterodimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of DNA Repair Regulation Of Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Response To Paraquat	Ovarian Follicle Development Regulation Of DNA Repair DNA-templated Transcription DNA-templated Transcription Initiation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Heart rate response to exercise ( 29769521)	Body mass index ( 28892062) Fasting glucose ( 33381925) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Red blood cell count ( 32888494) Response to fenofibrate (LDL cholesterol levels) ( 27002377)
Interacting Genes		14 interacting genes: ESR1 H3-4 PUF60 TAF1 TAF10 TAF11 TAF12 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 UBC	22 interacting genes: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 H3-4 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12
Entrez ID		6873	6874
HPRD ID		07060	11797
Ensembl ID		ENSG00000064313	ENSG00000130699
Uniprot IDs		A0A8I5KSY6 A0A8I5KV60 A0A8I5QJR0 B3KMD8 Q6P1X5	O00268
PDB IDs		5FUR 6MZC 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGH 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	1H3O 2P6V 6MZC 6MZD 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGG 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Preinitiation Complex Assembly Transcription Factor TFIID Complex Transcription Preinitiation Complex Assembly RNA Polymerase II General Transcription Initiation Factor Activity MRNA Transcription By RNA Polymerase II MRNA Transcription Protein-DNA Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Transcription Factor TFTC Complex Transcription By RNA Polymerase II DNA-templated Transcription Protein-containing Complex Assembly MRNA Metabolic Process Protein-containing Complex Organization Protein Heterodimerization Activity Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process MLL1 Complex Positive Regulation Of Transcription By RNA Polymerase II Cellular Component Assembly Regulation Of DNA Repair Macromolecule Biosynthetic Process Nucleic Acid Metabolic Process Nucleoplasm Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription SAGA Complex TBP-class Protein Binding Positive Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Nucleus Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone Acetyltransferase Activity Positive Regulation Of Metabolic Process	Transcription Factor TFIID Complex RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of DNA-templated Transcription Initiation RNA Polymerase II Preinitiation Complex Assembly Regulation Of DNA-templated Transcription Initiation Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Transcription Initiation By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter DNA-templated Transcription Initiation MRNA Transcription By RNA Polymerase II Protein-DNA Complex Assembly MRNA Transcription Positive Regulation Of Transcription By RNA Polymerase II Transcription Factor TFTC Complex Transcription By RNA Polymerase II Protein Heterodimerization Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process TBP-class Protein Binding Nucleoplasm Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Nucleus Protein-containing Complex Assembly Regulation Of Gene Expression Transcription Cis-regulatory Region Binding Regulation Of Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of Primary Metabolic Process Protein-containing Complex Organization Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of DNA Repair Regulation Of Macromolecule Metabolic Process SAGA Complex RNA Metabolic Process RNA Polymerase II General Transcription Initiation Factor Binding MLL1 Complex
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