SUPT6H and IWS1

Number of citations of the paper that reports this interaction (PMID 19141475)
51

Data Source:
BioGRID (pull down)

		SUPT6H	IWS1
Gene Name		suppressor of Ty 6 homolog (S. cerevisiae)	IWS1 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Histone Binding Poly(A) RNA Binding	DNA Binding Protein Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Viral Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Regulation Of Isotype Switching Regulation Of MRNA Processing MRNA Transport Regulation Of Muscle Cell Differentiation Negative Regulation Of Histone H3-K27 Methylation	Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Regulation Of MRNA Processing MRNA Transport Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CSNK2A1 ERBB2 IWS1	7 interactors: CSNK2A1 ERICH2 KRTAP10-3 POLR2A STAT2 SUPT6H TCEA1
Entrez ID		6830	55677
HPRD ID		03211	07639
Ensembl ID		ENSG00000109111	ENSG00000163166
Uniprot IDs		Q7KZ85	Q96ST2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Growth Regulation Of Histone H3-K36 Trimethylation Regulation Of Chromosome Organization Positive Regulation Of Growth Negative Regulation Of Immature T Cell Proliferation In Thymus Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Growth Axon Guidance Regulation Of Protein Metabolic Process Transcription, DNA-templated Negative Regulation Of T Cell Differentiation In Thymus Regulation Of MRNA Export From Nucleus RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase I Promoter Axonogenesis Regulation Of RNA Export From Nucleus Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Regulation Of Growth Regulation Of Histone H4 Acetylation Neuron Projection Morphogenesis Regulation Of Transcription From RNA Polymerase I Promoter RNA Metabolic Process Cell Morphogenesis Involved In Differentiation Regulation Of Transcription From RNA Polymerase III Promoter Phosphatidylinositol 3-kinase Signaling Gene Expression Neuron Projection Development Positive Regulation Of Cell Proliferation Cellular Macromolecule Biosynthetic Process Cell Projection Morphogenesis Regulation Of T Cell Differentiation In Thymus Macromolecule Biosynthetic Process Cell Part Morphogenesis Motor Neuron Axon Guidance Negative Regulation Of T Cell Differentiation Regulation Of Organelle Organization Neuron Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Negative Regulation Of Lymphocyte Differentiation Cell Morphogenesis Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Histone Acetylation Regulation Of Transcription, DNA-templated	Viral Process Transcription, DNA-templated RNA Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription Regulation Of DNA-templated Transcription, Elongation RNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Gene Expression Regulation Of Viral Transcription Cellular Macromolecule Biosynthetic Process Positive Regulation Of Viral Process Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Chromosome Organization Nucleotide-excision Repair Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Transcription, RNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Chromosome Organization Negative Regulation Of Histone H3-K27 Methylation Regulation Of MRNA Export From Nucleus Positive Regulation Of Metabolic Process RNA Splicing Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Export From Nucleus Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Histone H3-K27 Methylation MRNA Processing Regulation Of Metabolic Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Histone Methylation Regulation Of Transcription From RNA Polymerase II Promoter MRNA Metabolic Process RNA Processing Positive Regulation Of DNA-templated Transcription, Elongation DNA Repair 7-methylguanosine MRNA Capping
Tagcloud ?		19q13 aa acidic argues consensus differ end family homologue lacks like map maps member near q repeat respond ryanodine seven signals similarity spt5 spt6 terminus unlike w yeast	altogether cofactor competent eradication establishment hiv integrase integration investigating latent latently ledgf maintains occupancy p75 participates persistence postintegration provirus reactivation recruit represses reservoir serious silenced silent spt6 steps transcriptionally
Tagcloud (Difference) ?		19q13 aa acidic argues consensus differ end family homologue lacks like map maps member near q repeat respond ryanodine seven signals similarity spt5 terminus unlike w yeast	altogether cofactor competent eradication establishment hiv integrase integration investigating latent latently ledgf maintains occupancy p75 participates persistence postintegration provirus reactivation recruit represses reservoir serious silenced silent steps transcriptionally
Tagcloud (Intersection) ?		spt6