SUPT6H

Name	SPT6 homolog, histone chaperone and transcription elongation factor
Structure
Interactors	15 interactors: AKT1 CSNK2A1 DNAJB6 EGFR ERBB2 ERCC6 GAB1 HSP90B1 HSPA9 HSPD1 IWS1 MCPH1 RNF10 TCEA1 TSC2
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Elongation Factor Complex
	Molecular Function	Nucleic Acid Binding DNA Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding
	Biological Process	Blastocyst Formation Nucleobase-containing Compound Metabolic Process Transcription Elongation By RNA Polymerase II MRNA Processing RNA Splicing Positive Regulation Of Transcription Elongation By RNA Polymerase II Nucleosome Organization Regulation Of Isotype Switching MRNA Transport Regulation Of Muscle Cell Differentiation Transcription Elongation-coupled Chromatin Remodeling
Pathways	Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
GWAS	Pulse pressure ( 30578418 )
Entrez ID	6830
HPRD ID	03211
Ensembl ID	ENSG00000109111
Uniprot IDs	Q7KZ85
PDB IDs	6GME 6GMH 6TED 7OOP 7OPC 7OPD 7UNC 7UND 8A3Y 8OEU 8OEV 8OF0 9EGX 9EGY 9EGZ 9EH0 9EH2
GO Terms Enriched among Interactors ?	Protein Localization To Organelle Epidermal Growth Factor Receptor Signaling Pathway Intracellular Protein Localization ERBB Signaling Pathway Protein Folding Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Peptidyl-serine Phosphorylation Unfolded Protein Binding Negative Regulation Of Apoptotic Process ATP-dependent Protein Folding Chaperone Negative Regulation Of Programmed Cell Death ATP Binding Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Translational Initiation Positive Regulation Of Cell Growth Response To Epidermal Growth Factor Cellular Localization Positive Regulation Of Toll-like Receptor Signaling Pathway Protein Folding Chaperone ERBB2-EGFR Signaling Pathway Sperm Plasma Membrane Nucleotide Binding Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Metabolic Process Double-strand Break Repair Via Classical Nonhomologous End Joining Establishment Of Protein Localization Positive Regulation Of Phosphorylation Positive Regulation Of Growth Anoikis Response To UV-A Nuclear Transport Nucleocytoplasmic Transport Calcium Import Into The Mitochondrion Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cellular Response To Stress Intracellular Protein Transport Protein Tyrosine Kinase Activator Activity Regulation Of Apoptotic Process Regulation Of Translational Initiation Regulation Of RNA Metabolic Process Regulation Of Programmed Cell Death Mitochondrial Calcium Ion Transmembrane Transport Positive Regulation Of Phosphate Metabolic Process Regulation Of Wnt Signaling Pathway Establishment Of Localization In Cell Regulation Of Macromolecule Metabolic Process Establishment Of Protein Localization To Organelle Regulation Of Cell Cycle ERBB2 Signaling Pathway Protein Transport