IWS1

Description		interacts with SUPT6H, CTD assembly factor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	Protein Binding
	Biological Process	In Utero Embryonic Development Chromatin Remodeling MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus Regulation Of MRNA Processing MRNA Transport Transcription Elongation-coupled Chromatin Remodeling
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS		Cardiac troponin-I levels ( 31014085)
Novel Interacting Genes		1 novel interacting genes: SAP130
Interacting Genes		10 interacting genes: AKT1 AKT3 CSNK2A1 ERCC6 ERICH2 KRTAP10-3 POLR2A STAT2 SUPT6H TCEA1
Entrez ID		55677
HPRD ID		07639
Ensembl ID		ENSG00000163166
Uniprot IDs		A0A1B0GW95 Q96ST2
PDB IDs		6EMR 6ZV1 6ZV4 9EGX 9EGY 9EGZ 9EH0 9EH1 9EH2
Enriched GO Terms of Interacting Partners?		DNA-templated Transcription Elongation Transcription Elongation By RNA Polymerase II Negative Regulation Of PERK-mediated Unfolded Protein Response Double-strand Break Repair Via Classical Nonhomologous End Joining RNA Metabolic Process Regulation Of PERK-mediated Unfolded Protein Response Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of DNA Recombination Sin3-type Complex Transcription Elongation Factor Complex Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Execution Phase Of Apoptosis Regulation Of Peptidyl-serine Phosphorylation Regulation Of DNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Response To Stress Negative Regulation Of Double-strand Break Repair Negative Regulation Of DNA Repair Negative Regulation Of Translational Initiation Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Response To Endoplasmic Reticulum Stress Nucleoplasm Regulation Of TRNA Methylation Positive Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Via Nonhomologous End Joining Positive Regulation Of Blood Vessel Endothelial Cell Migration Nucleic Acid Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Response To Insulin-like Growth Factor Stimulus Regulation Of Blood Vessel Endothelial Cell Migration Protein Serine Kinase Activity Mammalian Oogenesis Stage Regulation Of Protein Phosphorylation Regulation Of Phosphorylation Regulation Of Gene Expression Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Regulation Of Cell Cycle Phase Transition Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Kinase Binding
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