IWS1 and TCEA1

Number of citations of the paper that reports this interaction (PMID 16648364)
7

Data Source:
HPRD (in vitro)

		IWS1	TCEA1
Gene Name		IWS1 homolog (S. cerevisiae)	transcription elongation factor A (SII), 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Nucleolus
	Molecular Function	DNA Binding Protein Binding	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of MRNA Export From Nucleus Regulation Of MRNA Processing MRNA Transport Regulation Of Histone H4 Acetylation Regulation Of Histone H3-K36 Trimethylation	DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Erythrocyte Differentiation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways			Nucleotide Excision Repair Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery Formation of transcription-coupled NER (TC-NER) repair complex RNA Polymerase II Pre-transcription Events Dual incision reaction in TC-NER Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription-coupled NER (TC-NER) HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CSNK2A1 ERICH2 KRTAP10-3 POLR2A STAT2 SUPT6H TCEA1	17 interactors: APP CDC73 CDK7 CIR1 CTDP1 CTR9 EAF2 GTF2E1 GTF2F2 IWS1 LEO1 PAF1 POLR2A REXO1 RTF1 UBR5 WDR61
Entrez ID		55677	6917
HPRD ID		07639	03252
Ensembl ID		ENSG00000163166	ENSG00000187735
Uniprot IDs		Q96ST2	B7Z4S1 P23193
PDB IDs			1TFI 3NDQ
Enriched GO Terms of Interacting Partners?		Viral Process Transcription, DNA-templated RNA Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription Regulation Of DNA-templated Transcription, Elongation RNA Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Gene Expression Regulation Of Viral Transcription Cellular Macromolecule Biosynthetic Process Positive Regulation Of Viral Process Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Chromosome Organization Nucleotide-excision Repair Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Transcription, RNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Chromosome Organization Negative Regulation Of Histone H3-K27 Methylation Regulation Of MRNA Export From Nucleus Positive Regulation Of Metabolic Process RNA Splicing Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Export From Nucleus Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Histone H3-K27 Methylation MRNA Processing Regulation Of Metabolic Process Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Histone Methylation Regulation Of Transcription From RNA Polymerase II Promoter MRNA Metabolic Process RNA Processing Positive Regulation Of DNA-templated Transcription, Elongation DNA Repair 7-methylguanosine MRNA Capping	Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Transcription Elongation From RNA Polymerase II Promoter Endodermal Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription, Elongation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated MRNA Processing Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Histone H2B Ubiquitination Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Cell Fate Commitment Involved In Formation Of Primary Germ Layer Positive Regulation Of Gene Expression MRNA Metabolic Process Gene Expression Positive Regulation Of Cellular Biosynthetic Process Endodermal Cell Differentiation RNA Processing Regulation Of Nitrogen Compound Metabolic Process Endoderm Formation Transcription Elongation From RNA Polymerase II Promoter Stem Cell Maintenance Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Elongation Negative Regulation Of Myeloid Cell Differentiation Endoderm Development MRNA Polyadenylation Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Histone Ubiquitination RNA Polyadenylation Negative Regulation Of Cell Differentiation Stem Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Protein Monoubiquitination Regulation Of Histone Modification Wnt Signaling Pathway Formation Of Primary Germ Layer Positive Regulation Of Viral Transcription
Tagcloud ?		altogether cofactor competent eradication establishment hiv integrase integration investigating latent latently ledgf maintains occupancy p75 participates persistence postintegration provirus reactivation recruit represses reservoir serious silenced silent spt6 steps transcriptionally	arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5
Tagcloud (Difference) ?		altogether cofactor competent eradication establishment hiv integrase integration investigating latent latently ledgf maintains occupancy p75 participates persistence postintegration provirus reactivation recruit represses reservoir serious silenced silent spt6 steps transcriptionally	arachnoid beforehand cdc25a cdk6 cluego cytoscape distinctive dysregulation helpful hub ifit ifit1 introduced mcm2 mcm7 mcode meningioma meningiomas meningothelial mined names neutralization ppi rbc sec31a seed subnetworks ube2e1 xrcc5
Tagcloud (Intersection) ?