BST1 and LBP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		BST1	LBP
Gene Name		bone marrow stromal cell antigen 1	lipopolysaccharide binding protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome	Extracellular Region Extracellular Space Cell Surface Extracellular Vesicular Exosome
	Molecular Function	NAD+ Nucleosidase Activity Transferase Activity Phosphorus-oxygen Lyase Activity NAD(P)+ Nucleosidase Activity	Lipopolysaccharide Binding Receptor Binding Protein Binding Lipoteichoic Acid Binding
	Biological Process	Humoral Immune Response Multicellular Organismal Development Metabolic Process Positive Regulation Of B Cell Proliferation	Toll-like Receptor Signaling Pathway Leukocyte Chemotaxis Involved In Inflammatory Response Macrophage Activation Involved In Immune Response Acute-phase Response Cellular Defense Response Opsonization Lipopolysaccharide Transport Lipopolysaccharide-mediated Signaling Pathway Detection Of Molecule Of Bacterial Origin Response To Lipopolysaccharide Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of Macrophage Activation Negative Regulation Of Growth Of Symbiont In Host Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Cellular Response To Lipopolysaccharide Cellular Response To Lipoteichoic Acid Positive Regulation Of Neutrophil Chemotaxis
Pathways			Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade Transfer of LPS from LBP carrier to CD14 Innate Immune System
Drugs		Adenosine-5\'-Diphosphate Monothiophosphate Etheno-Nad Nicotinamide Nicotinamide Mononucleotide Etheno-Nadp
Diseases
GWAS		Parkinson's disease ( 22451204 21084426 21292315 19915576)
Protein-Protein Interactions		2 interactors: CAV1 LBP	19 interactors: APOA1 BAG6 BST1 C4BPA CAMP CBFA2T2 CD14 CFHR1 FTH1 HSPB1 IRF6 PRDX4 PSMA3 PYCRL RPS21 SETD1A SMAD3 TRA2A TSC22D4
Entrez ID		683	3929
HPRD ID		02665	07175
Ensembl ID		ENSG00000109743	ENSG00000129988
Uniprot IDs		Q10588 Q1XII0	P18428 Q8TCF0
PDB IDs		1ISF 1ISG 1ISH 1ISI 1ISJ 1ISM
Enriched GO Terms of Interacting Partners?		Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Leukocyte Migration Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Lipopolysaccharide Transport Nitric Oxide Homeostasis Positive Regulation Of Cell Activation Lipid Transport Lipid Localization Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Mammary Gland Involution Regulation Of Cell Activation Protein Localization To Plasma Membrane Raft Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Metalloenzyme Activity Caveola Assembly Positive Regulation Of Respiratory Burst Regulation Of Cardiac Muscle Cell Action Potential Regulation Of The Force Of Heart Contraction By Chemical Signal Negative Regulation Of Nitric-oxide Synthase Activity Cellular Response To Hyperoxia Endocytosis Membrane Raft Assembly Regulation Of Cellular Component Movement Opsonization Protein Localization To Membrane Raft Regulation Of Respiratory Burst Macrophage Activation Involved In Immune Response Negative Regulation Of Monooxygenase Activity Positive Regulation Of Macrophage Activation Negative Regulation Of Protein Autophosphorylation Positive Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Cellular Response To Lipoteichoic Acid Detection Of Molecule Of Bacterial Origin Negative Regulation Of Anoikis Negative Regulation Of Nitric Oxide Biosynthetic Process Cell Migration Response To Lipid Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Leukocyte Migration Involved In Inflammatory Response Negative Regulation Of Protein Tyrosine Kinase Activity	Immune System Process Immune Response Regulation Of Interleukin-1 Beta Production Regulation Of Cell Proliferation Humoral Immune Response Protein Stabilization Response To Stress Regulation Of Protein Stability Positive Regulation Of Interleukin-1 Beta Production Regulation Of Protein Catabolic Process Positive Regulation Of Interleukin-1 Production Regulation Of Immune System Process Posttranscriptional Regulation Of Gene Expression Regulation Of Immune Response Positive Regulation Of Stress Fiber Assembly Response To Stimulus Negative Regulation Of Protein Metabolic Process Positive Regulation Of Actin Filament Bundle Assembly Gene Expression Regulation Of Cytokine Production Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Male Germ Cell Proliferation Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Growth Of Symbiont On Or Near Host Surface Regulation Of Protein Metabolic Process Positive Regulation Of Tumor Necrosis Factor Production I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Process Regulation Of Stress Fiber Assembly Regulation Of Inflammatory Response Negative Regulation Of Cell Proliferation Regulation Of Opsonization Intracellular Sequestering Of Iron Ion Negative Regulation Of Interleukin-1 Beta Secretion Sister Chromatid Biorientation Response To Other Organism Positive Regulation Of Protein Metabolic Process Epithelial Cell Proliferation Intracellular Signal Transduction Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Male Germ Cell Proliferation Evasion Or Tolerance Of Host Defenses By Virus Response To Biotic Stimulus Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cytokine Production Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Metabolic Process Negative Regulation Of Inflammatory Response
Tagcloud ?		20e abca7 additive apoe associations calculate clu coded cr1 ethnic fail genotyped gwas hits korean koreans logistic lrrk2 overlapping park16 pd picalm rab7l1 replicated rs11931074 snca snps susceptibility top	adopt af agonists allowing apo bms614 competent constitutive corepressor der disabled disrupts h11 heterodimerization heterodimers holo maintains modelling ngfi pocket relieve rxr rxralpha rxralphaf318a shifting thermodynamic transcriptionally van waals
Tagcloud (Difference) ?		20e abca7 additive apoe associations calculate clu coded cr1 ethnic fail genotyped gwas hits korean koreans logistic lrrk2 overlapping park16 pd picalm rab7l1 replicated rs11931074 snca snps susceptibility top	adopt af agonists allowing apo bms614 competent constitutive corepressor der disabled disrupts h11 heterodimerization heterodimers holo maintains modelling ngfi pocket relieve rxr rxralpha rxralphaf318a shifting thermodynamic transcriptionally van waals
Tagcloud (Intersection) ?