BST1

Name	bone marrow stromal cell antigen 1
Structure
Novel Interactors	1 novel interactors: PCDH7
Interactors	2 interactors: CAV1 LBP
GO Annotations	Cellular Component	Uropod Extracellular Region Plasma Membrane Membrane Specific Granule Membrane Extracellular Exosome Side Of Membrane
	Molecular Function	Transferase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Phosphorus-oxygen Lyase Activity NAD+ Nucleosidase Activity, Cyclic ADP-ribose Generating
	Biological Process	Regulation Of Cell-matrix Adhesion Regulation Of Cellular Extravasation Humoral Immune Response Signal Transduction Positive Regulation Of Cell Population Proliferation Positive Regulation Of B Cell Proliferation Regulation Of Actin Cytoskeleton Organization Regulation Of Inflammatory Response Regulation Of Calcium-mediated Signaling Regulation Of Neutrophil Chemotaxis Regulation Of Superoxide Metabolic Process Regulation Of Integrin-mediated Signaling Pathway
Pathways	Post-translational modification: synthesis of GPI-anchored proteins Nicotinate metabolism Neutrophil degranulation
Drugs	Etheno-NAD Nicotinamide Adenosine 5'-[gamma-thio]triphosphate Nicotinamide Mononucleotide Etheno-Nadp
GWAS	Blood protein levels ( 30072576 ) Current cigarettes per day in chronic obstructive pulmonary disease ( 21685187 ) Parkinson's disease ( 19915576 21084426 21292315 22451204 25064009 27182965 32201043 32310270 ) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892 ) Response to beta blocker use in hypertension (systolic blood pressure) ( 31423876 ) Urinary metabolite levels in chronic kidney disease ( 31959995 )
Entrez ID	683
HPRD ID	02665
Ensembl ID	ENSG00000109743
Uniprot IDs	Q10588
PDB IDs	1ISF 1ISG 1ISH 1ISI 1ISJ 1ISM
GO Terms Enriched among Interactors ?	Regulation Of Toll-like Receptor 4 Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Inward Rectifier Potassium Channel Inhibitor Activity Innate Immune Response-activating Signaling Pathway Insulin Receptor Internalization Protein Localization To Basolateral Plasma Membrane Intracellular Nitric Oxide Homeostasis Nitric-oxide Synthase Inhibitor Activity Caveolar Macromolecular Signaling Complex Activation Of Innate Immune Response Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Lipopolysaccharide Transport Regulation Of Entry Of Bacterium Into Host Cell Signaling Receptor Binding Peptidase Activator Activity Caveola Assembly Positive Regulation Of Cell Activation Protein Tyrosine Kinase Inhibitor Activity Protein Localization To Plasma Membrane Raft Positive Regulation Of Innate Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Caveolin-mediated Endocytosis Regulation Of Membrane Repolarization During Action Potential Response To Bacterium Protein Localization To Membrane Raft Lipid Transport Regulation Of Gap Junction Assembly Positive Regulation Of Gap Junction Assembly Negative Regulation Of Pinocytosis Mammary Gland Involution Patched Binding Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of The Force Of Heart Contraction By Chemical Signal Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Hyperoxia Immune Response-activating Signaling Pathway Positive Regulation Of Respiratory Burst Lipoteichoic Acid Binding Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Lipopeptide Binding Nitric-oxide Synthase Binding Receptor-mediated Endocytosis Of Virus By Host Cell Plasma Membrane Raft Assembly Regulation Of Innate Immune Response Regulation Of Ventricular Cardiac Muscle Cell Action Potential Immune Response-regulating Signaling Pathway Positive Regulation Of Defense Response