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PPIA
Gene Name
peptidylprolyl isomerase A (cyclophilin A)
Image
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Nucleus
Cytosol
Focal Adhesion
Membrane
Extracellular Vesicular Exosome
Molecular Function
Peptidyl-prolyl Cis-trans Isomerase Activity
Protein Binding
Peptide Binding
Poly(A) RNA Binding
Virion Binding
Unfolded Protein Binding
Biological Process
Protein Peptidyl-prolyl Isomerization
Platelet Degranulation
RNA-dependent DNA Replication
Protein Folding
Blood Coagulation
Viral Process
Viral Life Cycle
Uncoating Of Virus
Virion Assembly
Viral Release From Host Cell
Platelet Activation
Entry Into Host Cell
Lipid Particle Organization
Regulation Of Viral Genome Replication
Positive Regulation Of Viral Genome Replication
Positive Regulation Of Protein Secretion
Leukocyte Migration
Establishment Of Integrated Proviral Latency
Pathways
HIV Infection
Host Interactions of HIV factors
Integration of provirus
Platelet degranulation
Basigin interactions
Late Phase of HIV Life Cycle
Cell surface interactions at the vascular wall
Uncoating of the HIV Virion
Early Phase of HIV Life Cycle
Reverse Transcription of HIV RNA
Assembly Of The HIV Virion
HIV Life Cycle
Budding and maturation of HIV virion
Response to elevated platelet cytosolic Ca2+
Minus-strand DNA synthesis
Platelet activation, signaling and aggregation
Binding and entry of HIV virion
Plus-strand DNA synthesis
APOBEC3G mediated resistance to HIV-1 infection
Drugs
Cyclosporine
L-Proline
(3r)-1-Acetyl-3-Methylpiperidine
Ethyl Oxo(Piperidin-1-Yl)Acetate
(3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl-
Diseases
GWAS
Protein-protein Interactions
22 interactors:
APP
BSG
CD99
ITK
JAK2
LIG4
LNX1
NOTCH3
PAXIP1
PRLR
PRR13
PRSS23
PTPRN
RB1
S100A8
SRPK1
SRPK2
SUPT5H
TCF4
TERT
USP4
YY1
Entrez ID
5478
HPRD ID
00457
Ensembl ID
ENSG00000196262
Uniprot IDs
P62937
Q567Q0
PDB IDs
1AK4
1AWQ
1AWR
1AWS
1AWT
1AWU
1AWV
1BCK
1CWA
1CWB
1CWC
1CWF
1CWH
1CWI
1CWJ
1CWK
1CWL
1CWM
1CWO
1FGL
1M63
1M9C
1M9D
1M9E
1M9F
1M9X
1M9Y
1MF8
1MIK
1NMK
1OCA
1RMH
1VBS
1VBT
1W8L
1W8M
1W8V
1YND
1ZKF
2ALF
2CPL
2CYH
2RMA
2RMB
2X25
2X2A
2X2C
2X2D
2XGY
3CYH
3CYS
3K0M
3K0N
3K0O
3K0P
3K0Q
3K0R
3ODI
3ODL
3RDD
4CYH
5CYH
Enriched GO Terms of Interacting Partners
?
Chromosome Organization
RNA Metabolic Process
Activation Of JAK2 Kinase Activity
Cellular Metabolic Process
Positive Regulation Of Gene Expression
Immune System Process
RNA Processing
Cell Differentiation
Positive Regulation Of Metabolic Process
Response To Stress
Gene Expression
Regulation Of Gene Expression
Cellular Response To Stimulus
Activation Of Janus Kinase Activity
Neuron Apoptotic Process
Organ Development
Regulation Of RNA Metabolic Process
DNA Metabolic Process
Neuron Death
Chromatin Organization
Organelle Organization
MRNA Processing
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Viral Process
Response To Stimulus
Developmental Process
Protein Metabolic Process
Positive Regulation Of Peptide Secretion
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Innate Immune Response
Regulation Of Metabolic Process
Positive Regulation Of Protein Metabolic Process
Anatomical Structure Development
System Development
Regulation Of Nitrogen Compound Metabolic Process
Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Immune Response
MRNA Metabolic Process
Leukocyte Aggregation
Positive Regulation Of Proteolysis
Cellular Component Assembly
Chromatin Modification
Leukocyte Cell-cell Adhesion
Positive Regulation Of Viral Genome Replication
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Homotypic Cell-cell Adhesion
Response To Organic Substance
Tagcloud
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ape1
apparently
beetroot
breaks
cdkn2a
consumed
defenses
differing
formulations
gexp
gss
hdls
ho1
homeostatic
il6
interindividual
investigates
occasions
postprandial
ptgs2
saturated
scope
sirt
socs3
strand
stratified
ucp2
unsaturated
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