VAMP8

Gene Name		vesicle-associated membrane protein 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Lysosomal Membrane Early Endosome Cytosol Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Secretory Granule Membrane SNARE Complex Late Endosome Membrane Vesicle Azurophil Granule Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Mucin Granule
	Molecular Function	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Autophagic Vacuole Fusion Exocytosis Post-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion Protein Transport Regulation Of Endocytosis SNARE Complex Assembly Eosinophil Degranulation Neutrophil Degranulation Viral Entry Into Host Cell Membrane Organization Mucus Secretion Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Secretion By Cell Positive Regulation Of Histamine Secretion By Mast Cell
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Prostate cancer ( 21743467)
Protein-protein Interactions		12 interactors: CDC25A MLH1 NAPA SNAP23 SNAP25 STX1A STX3 STX4 STX7 UBE2G2 VAMP2 VAMP3
Entrez ID		8673
HPRD ID		04415
Ensembl ID		ENSG00000118640
Uniprot IDs		Q9BV40
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Membrane Fusion Organelle Fusion Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Neurotransmitter Secretion Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Neurotransmitter Transport Vesicle Docking Membrane Docking Organelle Localization Synaptic Vesicle Transport Membrane Organization Establishment Of Organelle Localization Exocytosis Establishment Of Vesicle Localization Vesicle Localization Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Secretion By Cell Positive Regulation Of Synaptic Transmission Cell-cell Signaling Vesicle-mediated Transport Regulation Of Synaptic Transmission Synaptic Transmission Regulation Of Cellular Localization Cellular Localization Secretion Long-term Synaptic Potentiation Protein Transport Intracellular Protein Transport Establishment Of Protein Localization Organelle Organization Intracellular Transport Golgi Vesicle Transport Glutamate Secretion Regulation Of Secretion Cellular Protein Complex Assembly Protein Localization Regulation Of Exocytosis Regulation Of Protein Localization Regulation Of Synaptic Plasticity Cellular Protein Localization Calcium Ion-dependent Exocytosis Regulation Of Protein Localization To Plasma Membrane Regulation Of Insulin Secretion Regulation Of Synaptic Vesicle Priming Regulation Of Peptide Hormone Secretion Acid Secretion
Tagcloud ?		3t3 adipocytes characterised complexes consists facet finding fulfil glut4 immunoprecipitation isoforms l1 others propose sds snap23 snare subcellular syntaxin4 systematic trafficking vamp2 vamp3 vamps vary vesicle vesicles