CPLX2 and STX3

Number of citations of the paper that reports this interaction (PMID 8824312)
25

Data Source:
HPRD (in vitro, in vivo)

		CPLX2	STX3
Gene Name		complexin 2	syntaxin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Dendrite Mast Cell Granule Neuronal Cell Body Synapse Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Synaptobrevin 2-SNAP-25-syntaxin-3-complexin Complex	Vacuole Plasma Membrane Cell-cell Junction Synaptic Vesicle Integral Component Of Membrane Apical Plasma Membrane Lamellipodium Dendrite Growth Cone SNARE Complex Specific Granule Azurophil Granule Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	Syntaxin-1 Binding Calcium-dependent Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Arachidonic Acid Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Nervous System Development Synaptic Vesicle Exocytosis Regulation Of Exocytosis Cell Differentiation Positive Regulation Of Synaptic Plasticity Mast Cell Degranulation	Intracellular Protein Transport Positive Regulation Of Cell Proliferation Neuron Projection Development Synaptic Vesicle Fusion To Presynaptic Membrane Positive Regulation Of Cell Adhesion Vesicle Docking Positive Regulation Of Chemotaxis Long-term Synaptic Potentiation Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: APP STX2 STX3	17 interactors: CPLX2 NAPB SNAP23 SNAP25 SNAP29 STX4 STXBP1 STXBP2 SYT1 SYT4 SYT7 TRPC3 TXLNA VAMP2 VAMP3 VAMP7 VAMP8
Entrez ID		10814	6809
HPRD ID		09234	15985
Ensembl ID		ENSG00000145920	ENSG00000166900
Uniprot IDs		Q6PUV4	E7ET77 Q13277 Q53YE2
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Fusion To Presynaptic Membrane Exocytosis Secretion By Cell Vesicle Fusion Synaptic Vesicle Exocytosis Secretion Organelle Fusion Vesicle Docking Membrane Docking Neurotransmitter Secretion Synaptic Vesicle Transport Membrane Fusion Regulation Of Neurotransmitter Levels Neurotransmitter Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle-mediated Transport Vesicle Localization Synaptic Growth At Neuromuscular Junction Intracellular Transport Collateral Sprouting In Absence Of Injury Establishment Of Organelle Localization Collateral Sprouting Axon Midline Choice Point Recognition Establishment Of Localization In Cell Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Protein Localization To Cell Surface Organelle Localization Response To Oxidative Stress Cellular Localization Neuron Remodeling Synaptic Transmission Cellular Copper Ion Homeostasis Regulation Of Protein Localization To Cell Surface Copper Ion Homeostasis Suckling Behavior Response To Hydroperoxide Cell Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Ectoderm Development Acrosome Reaction Positive Regulation Of Protein Localization To Plasma Membrane Sexual Reproduction Neuron Projection Development Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Membrane Organization Mating Behavior	Exocytosis Secretion By Cell Secretion Neurotransmitter Secretion Regulation Of Neurotransmitter Levels Vesicle-mediated Transport Regulation Of Exocytosis Neurotransmitter Transport Vesicle Fusion Membrane Fusion Establishment Of Localization In Cell Organelle Fusion Regulation Of Secretion Synaptic Vesicle Exocytosis Cellular Localization Synaptic Vesicle Transport Regulation Of Cellular Localization Vesicle Organization Regulation Of Vesicle-mediated Transport Vesicle Docking Membrane Docking Establishment Of Vesicle Localization Vesicle Localization Membrane Organization Positive Regulation Of Exocytosis Transport SNARE Complex Assembly Establishment Of Organelle Localization Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Regulated Secretory Pathway Leukocyte Degranulation Cell-cell Signaling Organelle Localization Cell Activation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Regulation Of Hormone Secretion Glutamate Secretion Cellular Protein Complex Assembly Synaptic Transmission Protein Transport Protein Complex Assembly Establishment Of Protein Localization Positive Regulation Of Transport Golgi Vesicle Transport Synaptic Vesicle Priming Regulation Of Synaptic Transmission Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Secretion
Tagcloud ?		bases clones codes complexin correspond deduced department earlier evolutionarily exact exon exons far fragment genetics hfb1 hmob3 hmob33 institute libraries map1b mapped mob proved sequenced silico transmembrane unknown untranslated	cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx4 stx6 stx7 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b
Tagcloud (Difference) ?		bases clones codes complexin correspond deduced department earlier evolutionarily exact exon exons far fragment genetics hfb1 hmob3 hmob33 institute libraries map1b mapped mob proved sequenced silico transmembrane unknown untranslated	cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx4 stx6 stx7 stx8 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b
Tagcloud (Intersection) ?