TUBB4A and SELENOF

Number of citations of the paper that reports this interaction (PubMedID 29410696)
39

Data Source:
BioGRID (two hybrid)

		TUBB4A	SELENOF
Description		tubulin beta 4A class IVa	selenoprotein F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoskeleton Microtubule Cilium Axoneme Microtubule Cytoskeleton Internode Region Of Axon Cell Projection Neuronal Cell Body Myelin Sheath Intercellular Bridge Extracellular Exosome Mitotic Spindle	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Nucleotide Binding GTPase Activity Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding GTP Binding Metal Ion Binding	Protein Binding Thioredoxin Peroxidase Activity Selenium Binding Oxidoreductase Activity
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule-based Process Negative Regulation Of Microtubule Polymerization	Sperm DNA Condensation 'de Novo' Post-translational Protein Folding Cellular Oxidant Detoxification
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Anchoring of the basal body to the plasma membrane Cargo trafficking to the periciliary membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins PKR-mediated signaling
Drugs		Epothilone D Patupilone CYT997 ZEN-012 Artenimol
Diseases
GWAS		Left-handedness ( 32989287) Left–right brain asymmetry ( 33723403)
Interacting Genes		15 interacting genes: BMPR2 CEBPA CLN8 FNDC3B LINC01554 NEAT1 NR4A1 OGT RBM11 RSPH1 SELENOF STAU1 STK11 SUMO2 YWHAG	8 interacting genes: AGTR1 BAMBI RDH11 SEPTIN3 TUBB4A UGGT1 UGGT2 XRCC6
Entrez ID		10382	9403
HPRD ID		04045	09376
Ensembl ID		ENSG00000104833	ENSG00000183291
Uniprot IDs		M0QZL7 M0R1I1 M0R278 P04350	O60613
PDB IDs
Enriched GO Terms of Interacting Partners?		Non-canonical Inflammasome Complex Assembly LncRNA-mediated Post-transcriptional Gene Silencing Cellular Developmental Process	UDP-glucose:glycoprotein Glucosyltransferase Activity UDP-glucosylation UDP-alpha-D-glucose Metabolic Process Endoplasmic Reticulum Mannose Trimming Protein Alpha-1,2-demannosylation Protein Deglycosylation Protein N-linked Glycosylation Via Asparagine Endoplasmic Reticulum Quality Control Compartment Nucleotide-sugar Metabolic Process Angiotensin Type I Receptor Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Protein N-linked Glycosylation Bradykinin Receptor Binding Aldehyde Dehydrogenase (NADP+) Activity 11-cis-retinol Dehydrogenase (NADP+) Activity Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production DNA End Binding Ku70:Ku80 Complex Unfolded Protein Binding Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Cellular Hyperosmotic Salinity Response DNA-dependent Protein Kinase Complex Internode Region Of Axon Protein Glycosylation Glycosylation Macromolecule Glycosylation 'de Novo' Post-translational Protein Folding Hyperosmotic Salinity Response DNA-dependent Protein Kinase-DNA Ligase 4 Complex 5'-deoxyribose-5-phosphate Lyase Activity Glycosyltransferase Activity Regulation Of Renal Sodium Excretion Nonhomologous End Joining Complex Glycoprotein Biosynthetic Process Cellular Response To X-ray Nuclear Telomere Cap Complex Cellular Response To Salt Stress Protein-containing Complex Double-stranded Telomeric DNA Binding Type II Transforming Growth Factor Beta Receptor Binding All-trans-retinol Dehydrogenase (NADP+) Activity 'de Novo' Protein Folding Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Double-strand Break Repair Via Classical Nonhomologous End Joining Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Cell Differentiation Microtubule Cytoskeleton Cellular Detoxification Of Aldehyde
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