CMTM4 and STAR

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CMTM4	STAR
Description		CKLF like MARVEL transmembrane domain containing 4	steroidogenic acute regulatory protein
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Cholesterol Binding Cholesterol Transfer Activity
	Biological Process		Lipid Metabolic Process Steroid Biosynthetic Process Lipid Transport Cholesterol Metabolic Process Glucocorticoid Metabolic Process Intracellular Cholesterol Transport Regulation Of Steroid Biosynthetic Process Positive Regulation Of Bile Acid Biosynthetic Process
Pathways			Pregnenolone biosynthesis Mitochondrial protein degradation
Drugs
Diseases			Congenital adrenal hyperplasia (CAH) 46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS)
GWAS			Menopause (age at onset) ( 26414677) Orthostatic hypotension ( 24124408) Schizophrenia ( 29483656)
Interacting Genes		20 interacting genes: APOA4 APPL1 COQ8A DAPK1 DGCR6L DIABLO HSBP1L1 MIDN MRPL2 PBX3 PTPN9 SMG9 SNX1 SPG21 SSX3 STAR TBRG4 TCEA2 TTPA ZFYVE21	12 interacting genes: AGTRAP CCHCR1 CMTM4 DGAT2L6 FEZ1 LIPE MAGEA11 MAPK3 NUCB2 RABEP1 SMPD2 STX8
Entrez ID		146223	6770
HPRD ID		07435	02794
Ensembl ID		ENSG00000183723	ENSG00000147465
Uniprot IDs		Q8IZR5	P49675 Q6IBK0
PDB IDs			3P0L 5OMA 6T5F 6T5H
Enriched GO Terms of Interacting Partners?			Caveola
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