SSTR2 and CORT

Number of citations of the paper that reports this interaction (PMID 9125122)
5

Data Source:
BioGRID (unspecified method)
HPRD (in vivo)

		SSTR2	CORT
Gene Name		somatostatin receptor 2	cortistatin
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Extracellular Space
	Molecular Function	Somatostatin Receptor Activity Protein Binding PDZ Domain Binding Neuropeptide Binding	G-protein Coupled Receptor Binding Neuropeptide Hormone Activity
	Biological Process	Regulation Of Muscle Contraction G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Cell-cell Signaling Synaptic Transmission Spermatogenesis Response To Nutrient Digestion Negative Regulation Of Cell Proliferation Cerebellum Development Peristalsis Forebrain Development Somatostatin Signaling Pathway Response To Starvation Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus	Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Synaptic Transmission
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APP CORT GNA14 GNAI1 PIK3R1 PTPN6 SHANK1 SHANK2 SST	7 interactors: GHSR MRGPRX2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
Entrez ID		6752	1325
HPRD ID		01674	04150
Ensembl ID			ENSG00000241563
Uniprot IDs		P30874	O00230 Q8IUV6
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cell Activation Response To Wounding Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Vocalization Behavior Learning G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Surface Receptor Signaling Pathway Adult Behavior G-protein Coupled Receptor Signaling Pathway Synapse Organization Growth Hormone Receptor Signaling Pathway Synaptic Transmission Cellular Response To Growth Hormone Stimulus Signaling Cell Communication Social Behavior Response To Growth Hormone Learning Or Memory Cognition Response To Organonitrogen Compound Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cell-cell Signaling Response To Hormone Apoptotic Process Programmed Cell Death T Cell Costimulation Neuromuscular Process Controlling Balance Synapse Assembly Determination Of Affect NFAT Protein Import Into Nucleus Cell Death Death Associative Learning Response To Stress Single-organism Behavior Response To Peptide Hormone Signal Transduction Response To Peptide Abortive Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Transcription Factor Import Into Nucleus Regulation Of Receptor Activity Memory Neuromuscular Process Cellular Response To Hormone Stimulus	Somatostatin Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Estradiol Stimulus Neuropeptide Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Estrogen Stimulus G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Response To Peptide Hormone Cellular Response To Organonitrogen Compound Cellular Response To Steroid Hormone Stimulus Response To Peptide G-protein Coupled Receptor Signaling Pathway Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Cellular Response To Hormone Stimulus Response To Organonitrogen Compound Cell-cell Signaling Response To Estradiol Cellular Response To Organic Cyclic Compound Response To Hormone Cellular Response To Lipid Response To Glucocorticoid Response To Steroid Hormone Response To Corticosteroid Synaptic Transmission Response To Estrogen Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Response To Lipid Response To Organic Cyclic Compound Cellular Response To Organic Substance Response To Nutrient Levels Cerebellum Development Forebrain Development Response To Extracellular Stimulus Metencephalon Development Response To Organic Substance Hindbrain Development Response To Starvation Regulation Of Cell Proliferation Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Signal Transduction Brain Development Head Development Multicellular Organismal Reproductive Process Regulation Of Hormone Secretion Signaling Multicellular Organism Reproduction
Tagcloud ?		analogue appropriate braf cancers detecting dish entero extensive gastro give gives highlighted humanized immunohistochemistry kras list mutational nets neuroendocrine next ngs octreotide others particular pathologists perform rapidy somatostatin suitable	b10 beta2 bioassays cleft clefts congenic corticosteroid dynamical dysmorphogenesis e14 fraser iir juriloff learn logic malformation outline palatal palate palates palatogenesis plasmin plasminogen proposes rules sequester slower tgf urokinase
Tagcloud (Difference) ?		analogue appropriate braf cancers detecting dish entero extensive gastro give gives highlighted humanized immunohistochemistry kras list mutational nets neuroendocrine next ngs octreotide others particular pathologists perform rapidy somatostatin suitable	b10 beta2 bioassays cleft clefts congenic corticosteroid dynamical dysmorphogenesis e14 fraser iir juriloff learn logic malformation outline palatal palate palates palatogenesis plasmin plasminogen proposes rules sequester slower tgf urokinase
Tagcloud (Intersection) ?