SST and SSTR5

Number of citations of the paper that reports this interaction (PubMedID 7908405)
0

Data Source:
HPRD (in vivo)

		SST	SSTR5
Description		somatostatin	somatostatin receptor 5
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Neuronal Cell Body GABA-ergic Synapse Neuronal Dense Core Vesicle	Plasma Membrane Membrane Neuron Projection
	Molecular Function	Hormone Activity Protein Binding Identical Protein Binding Receptor Ligand Activity	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Protein Binding Neuropeptide Binding
	Biological Process	Hyperosmotic Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Response To Nutrient Digestion Negative Regulation Of Cell Population Proliferation Hormone-mediated Apoptotic Signaling Pathway Response To Xenobiotic Stimulus Response To Acidic PH Regulation Of Cell Migration Somatostatin Signaling Pathway Response To Amino Acid Response To Steroid Hormone Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels	Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cytokinesis Somatostatin Signaling Pathway Glucose Homeostasis Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates transcription of neuronal ligands	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Vapreotide Pasireotide Lanreotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS		Pursuit maintenance gain ( 29064472) Skin pigmentation ( 28300201)	Logical memory (immediate recall) in normal cognition ( 29274321) Polycystic ovary syndrome ( 25574032)
Interacting Genes		6 interacting genes: PDIA2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5	9 interacting genes: ADCY10 CNR1 CORT DRD2 GOPC PDZK1 PEX5 SST SSTR1
Entrez ID		6750	6755
HPRD ID		08920	01677
Ensembl ID		ENSG00000157005	ENSG00000162009
Uniprot IDs		P61278	P35346
PDB IDs		2MI1 7T10 7WIC 7WJ5 7XAT 7XMR 7XMS 7Y27	8X8L 8X8N 8ZBE 8ZCJ
Enriched GO Terms of Interacting Partners?		Somatostatin Receptor Activity Somatostatin Signaling Pathway Neuropeptide Binding G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Neuron Projection Hormone-mediated Signaling Pathway G Protein-coupled Receptor Activity Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Negative Regulation Of Cell Population Proliferation G Protein-coupled Receptor Signaling Pathway Cellular Response To Steroid Hormone Stimulus Response To Glucocorticoid Cellular Response To Lipid Response To Corticosteroid Response To Steroid Hormone Cellular Response To Estradiol Stimulus Response To Lipid Regulation Of Cell Population Proliferation Cellular Response To Hormone Stimulus Response To Estradiol Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Response To Hormone Hormone-mediated Apoptotic Signaling Pathway RNA Strand Annealing Activity Nuclear Pore Localization Intracellular Membraneless Organelle Protein Retention In ER Lumen Positive Regulation Of Long-term Neuronal Synaptic Plasticity Disulfide Oxidoreductase Activity Nuclear Pore Complex Assembly Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Maintenance Of Protein Localization In Endoplasmic Reticulum Protein Folding In Endoplasmic Reticulum Nuclear Pore Organization Costamere Ribonucleoprotein Granule Translation Regulator Activity Regulation Of Circadian Sleep/wake Cycle, Sleep Pore Complex Assembly Skeletal Muscle Organ Development Protein Disulfide Isomerase Activity	G Protein-coupled Receptor Signaling Pathway Somatostatin Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Trans-synaptic Signaling Synaptic Signaling GABA-ergic Synapse Regulation Of Monoatomic Anion Transport Positive Regulation Of Developmental Growth Positive Regulation Of Multicellular Organism Growth Signaling Cell-cell Signaling Telencephalon Cell Migration Positive Regulation Of Growth Forebrain Cell Migration Cell Communication G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Regulation Of Developmental Growth Regulation Of Multicellular Organism Growth Bicarbonate Binding Negative Regulation Of Anion Channel Activity Cannabinoid Receptor Activity G Protein-coupled Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Forebrain Development Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Negative Regulation Of Cardiac Muscle Cell Contraction Neuron Projection Retraction Positive Regulation Of Skeletal Muscle Satellite Cell Differentiation Protein Propionyltransferase Activity Axon Cannabinoid Signaling Pathway Retrograde Trans-synaptic Signaling By Endocannabinoid Synapse Regulation Of Monoatomic Ion Transport Dopamine Neurotransmitter Receptor Activity, Coupled Via Gi/Go Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Orbitofrontal Cortex Development Regulation Of Protein Localization Negative Regulation Of Dopamine Receptor Signaling Pathway Peroxisome Targeting Sequence Binding Central Region Of Growth Cone Hormone Activity Neuromuscular Process Response To Estradiol Negative Regulation Of Circadian Sleep/wake Cycle, Sleep Dendrite
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?