SST

Description		somatostatin
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytosol Neuronal Cell Body GABA-ergic Synapse Neuronal Dense Core Vesicle
	Molecular Function	Hormone Activity Protein Binding Identical Protein Binding Receptor Ligand Activity
	Biological Process	Hyperosmotic Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Chemical Synaptic Transmission Response To Nutrient Digestion Negative Regulation Of Cell Population Proliferation Hormone-mediated Apoptotic Signaling Pathway Response To Xenobiotic Stimulus Response To Acidic PH Regulation Of Cell Migration Somatostatin Signaling Pathway Response To Amino Acid Response To Steroid Hormone Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events MECP2 regulates transcription of neuronal ligands
Drugs
Diseases
GWAS		Pursuit maintenance gain ( 29064472) Skin pigmentation ( 28300201)
Novel Interacting Genes		1 novel interacting genes: FXR1
Interacting Genes		6 interacting genes: PDIA2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5
Entrez ID		6750
HPRD ID		08920
Ensembl ID		ENSG00000157005
Uniprot IDs		P61278
PDB IDs		2MI1 7T10 7WIC 7WJ5 7XAT 7XMR 7XMS 7Y27
Enriched GO Terms of Interacting Partners?		Somatostatin Receptor Activity Somatostatin Signaling Pathway Neuropeptide Binding G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Neuron Projection Hormone-mediated Signaling Pathway G Protein-coupled Receptor Activity Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Negative Regulation Of Cell Population Proliferation G Protein-coupled Receptor Signaling Pathway Cellular Response To Steroid Hormone Stimulus Response To Glucocorticoid Cellular Response To Lipid Response To Corticosteroid Response To Steroid Hormone Cellular Response To Estradiol Stimulus Response To Lipid Regulation Of Cell Population Proliferation Cellular Response To Hormone Stimulus Response To Estradiol Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Response To Hormone Hormone-mediated Apoptotic Signaling Pathway RNA Strand Annealing Activity Nuclear Pore Localization Intracellular Membraneless Organelle Protein Retention In ER Lumen Positive Regulation Of Long-term Neuronal Synaptic Plasticity Disulfide Oxidoreductase Activity Nuclear Pore Complex Assembly Negative Regulation Of Long-term Synaptic Potentiation Positive Regulation Of MiRNA-mediated Gene Silencing Maintenance Of Protein Localization In Endoplasmic Reticulum Protein Folding In Endoplasmic Reticulum Nuclear Pore Organization Costamere Ribonucleoprotein Granule Translation Regulator Activity Regulation Of Circadian Sleep/wake Cycle, Sleep Pore Complex Assembly Skeletal Muscle Organ Development Protein Disulfide Isomerase Activity
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