SRP72 and SULT2B1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SRP72	SULT2B1
Description		signal recognition particle 72	sulfotransferase family 2B member 1
Image
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle Ribonucleoprotein Complex	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Extracellular Exosome
	Molecular Function	RNA Binding Signal Recognition Particle Binding Protein Binding 7S RNA Binding TPR Domain Binding Ribosome Binding	Nucleic Acid Binding Alcohol Sulfotransferase Activity Protein Binding Sulfotransferase Activity Cholesterol Binding Transferase Activity Small Molecule Binding Steroid Sulfotransferase Activity Cholesterol Sulfotransferase Activity Steroid Hormone Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane	Lipid Metabolic Process Steroid Metabolic Process Cholesterol Metabolic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Epidermal Cell Differentiation 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane
Drugs			Adenosine 3',5'-diphosphate Pregnenolone N-cyclohexyltaurine
Diseases
GWAS		Airflow obstruction ( 22837378)	Elevated serum carcinoembryonic antigen levels ( 24941225) Non-oily fish consumption ( 32066663) Resting metabolic rate ( 28476931)
Interacting Genes		12 interacting genes: CASP3 CASP6 CDC42 CEBPA FCHSD2 HSPB1 OGT PYGM SKIL SRP68 SULT2B1 TULP3	12 interacting genes: ACYP2 DDIT4L FLACC1 KLHL8 PRICKLE3 REL SRP72 SULT1A1 SULT1B1 SULT1C3 SULT1E1 ZNF497
Entrez ID		6731	6820
HPRD ID		03671	04991
Ensembl ID		ENSG00000174780	ENSG00000088002
Uniprot IDs		O76094 V9HWK0	O00204
PDB IDs		5M72 5M73 5WRV 5WRW 7NFX 8QVW 8QVX	1Q1Q 1Q1Z 1Q20 1Q22
Enriched GO Terms of Interacting Partners?		Cellular Response To Staurosporine Pyroptotic Inflammatory Response Epithelial Cell Differentiation Multicellular Organismal-level Homeostasis Endothelin Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Chemotaxis Protein-containing Complex Binding Epithelial Cell Maturation Positive Regulation Of Chemotaxis Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Regulation Of Necroptotic Process Embryonic Organ Development Cellular Response To Alkaloid Signal Transduction Intrinsic Apoptotic Signaling Pathway Anatomical Structure Formation Involved In Morphogenesis Homeostatic Process Protein Processing Regulation Of Programmed Necrotic Cell Death Positive Regulation Of Developmental Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Phosphatidylinositol-3,4,5-trisphosphate Binding Regulation Of Programmed Cell Death Cytoplasm Epithelial Cell Apoptotic Process Inflammatory Response Cellular Developmental Process Response To Cytokine Positive Regulation Of Organelle Organization Regulation Of Cell Migration Macrophage Differentiation Protein Domain Specific Binding RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cell Tip Growth Hormonal Regulation Of The Force Of Heart Contraction Regulation Of Chemotaxis Lung Alveolus Development Negative Regulation Of Protein Kinase C Signaling Positive Regulation Of Nitric Oxide-cGMP Mediated Signal Transduction Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Stereocilium Shaft Epithelium Development Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Migration Response To Peptide Regulation Of Cell Motility Vasculature Development	Aryl Sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation Sulfotransferase Activity Ethanol Catabolic Process Ethanol Metabolic Process Flavonol 3-sulfotransferase Activity Alcohol Catabolic Process Steroid Sulfotransferase Activity Sulfur Compound Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Binding Flavonoid Metabolic Process Purine Ribonucleotide Metabolic Process Alcohol Metabolic Process Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Xenobiotic Metabolic Process Purine Nucleotide Metabolic Process Thyroid Hormone Metabolic Process Nucleotide Metabolic Process Estrogen Metabolic Process Purine-containing Compound Metabolic Process Hormone Metabolic Process Nucleoside Phosphate Metabolic Process Steroid Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Estrogen Catabolic Process Estrone Sulfotransferase Activity Biogenic Amine Metabolic Process Acylphosphatase Activity Organic Acid Metabolic Process Amine Metabolic Process Bile-salt Sulfotransferase Activity Phosphate-containing Compound Metabolic Process Carbohydrate Derivative Metabolic Process Phenol-containing Compound Metabolic Process Alcohol Sulfotransferase Activity NF-kappaB Complex Organophosphate Metabolic Process Cytoplasm Signal Recognition Particle 7S RNA Binding Outer Dense Fiber Signal Recognition Particle Binding Signal Recognition Particle, Endoplasmic Reticulum Targeting TPR Domain Binding Regulation Of Hormone Levels Modified Amino Acid Metabolic Process Dopamine Catabolic Process Catecholamine Catabolic Process
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