SRP72

Gene Name		signal recognition particle 72kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Endoplasmic Reticulum Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Plasma Membrane
	Molecular Function	Signal Recognition Particle Binding 7S RNA Binding Poly(A) RNA Binding
	Biological Process	Translation SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Response To Drug Cellular Protein Metabolic Process
Pathways		Translation SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378)
Protein-protein Interactions		5 interactors: CASP3 CASP6 FCHSD2 SKIL SRP68
Entrez ID		6731
HPRD ID		03671
Ensembl ID
Uniprot IDs		O76094
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epithelial Cell Differentiation Lymphocyte Homeostasis Execution Phase Of Apoptosis Leukocyte Homeostasis Epithelium Development Homeostasis Of Number Of Cells Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Glial Cell Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Tissue Development Protein Heterotrimerization Negative Regulation Of Activated T Cell Proliferation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Negative Regulation Of Cell Cycle Negative Regulation Of B Cell Proliferation Protein Homotrimerization Apoptotic DNA Fragmentation Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Platelet Formation Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Programmed Cell Death Response To Growth Factor Platelet Morphogenesis Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Cell Death Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Hippo Signaling Response To Cytokine Apoptotic Nuclear Changes Release Of Cytochrome C From Mitochondria Lens Fiber Cell Differentiation Protein Trimerization Regulation Of Activated T Cell Proliferation B Cell Homeostasis T Cell Homeostasis Negative Regulation Of B Cell Activation
Tagcloud ?		aa alongside aplastic associate autosomal causative coimmunoprecipitation dominant elucidating epitope excreted exome haplotype heterozygous idiopathic incorrectly inheritance inherited localize myelodysplasia nascent particle pathophysiology screen simplex snp tagged telomerase